Anti-IL-36RN Antibody

IL-36Ra/IL-1F5 antibody

Boster Bio Anti-IL-36RN Antibody (Catalog # A03455-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A03455-1
Size: 0.1 mg
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-IL-36RN Antibody

View all IL-36Ra/IL-1F5 Antibodies

SKU/Catalog Number

A03455-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-IL-36RN Antibody (Catalog # A03455-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

IL-36RN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-IL-36RN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03455-1)

Host

Rabbit

Contents

IL-36RN antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

IL-36RN antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IL-36RN. The immunogen is located within the last 50 amino acids of IL-36RN.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

IL-36RN antibody is human and mouse reactive. At least two isoforms of IL-36RN are known to exist

Reactive Species

A03455-1 is reactive to IL36RN in Human, Mouse

Applications

A03455-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

16.962kDa

Background of IL-36Ra/IL-1F5

IL-36RN is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36RN specifically inhibits the activation of NF-kappaB induced IL-36A (2). The opposing activities of these cytokines have been suggested to be involved in the regulation of skin inflammation (3). Like the IL-36 cytokines (IL-36A, IL-36B and IL-36G), IL-36RN requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IL-36RN antibody can be used for detection of IL-36RN by Western blot at 1 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For IL36RN (Source: Uniprot.org, NCBI)

Gene Name

IL36RN

Full Name

Interleukin-36 receptor antagonist protein

Weight

16.962kDa

Superfamily

IL-1 family

Alternative Names

FIL1 delta; FIL1; FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta); FIL1DIL-1 delta; IL1F5 (Canonical product IL-1F5a); IL1F5; IL-1HY1; IL-1L1; IL-1RP3; IL36Ra; IL-36Ra; IL36RN; interleukin 1 family, member 5 (delta); interleukin 1, delta; Interleukin 36 Receptor Antagonist; interleukin-1 family member 5; Interleukin-1 HY1; Interleukin-1 receptor antagonist homolog 1; Interleukin-1-like protein 1; Interleukin-36 Receptor Antagonist IL36RN FIL1, FIL1(DELTA), FIL1D, IL-36Ra, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, PSORP, PSORS14 interleukin 36 receptor antagonist interleukin-36 receptor antagonist protein|IL-1 related protein 3|IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta)|IL-1ra homolog 1|IL1F5 (Canonical product IL-1F5a)|interleukin 1 family, member 5 (delta)|interleukin-1 HY1|interleukin-1 receptor antagonist homolog 1|interleukin-1-like protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on IL36RN, check out the IL36RN Infographic

IL36RN infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IL36RN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A03455-1-0.1 mg

0.1 mg

$449

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