Anti-IL2 Receptor gamma/IL2RG Antibody Picoband™

Common gamma Chain/IL-2 R gamma antibody

Boster Bio Anti-IL2 Receptor gamma/IL2RG Antibody Picoband™ catalog # A00308-1. Tested in IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A00308-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, ICC, WB

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Product Name

Anti-IL2 Receptor gamma/IL2RG Antibody Picoband™

View all Common gamma Chain/IL-2 R gamma Antibodies

SKU/Catalog Number

A00308-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-IL2 Receptor gamma/IL2RG Antibody Picoband™ catalog # A00308-1. Tested in IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IL2 Receptor gamma/IL2RG Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00308-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human IL2 Receptor gamma/IL2RG, which shares 78.9% amino acid (aa) sequence identity with both mouse and rat IL2 Receptor gamma/IL2RG.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00308-1 is reactive to IL2RG in Human, Mouse, Rat

Applications

A00308-1 is guaranteed for IF, ICC, WB Boster Guarantee

Observed Molecular Weight

65 kDa

Calculated molecular weight

42.287kDa

Background of Common gamma Chain/IL-2 R gamma

IL2RG (INTERLEUKIN 2 RECEPTOR, GAMMA),also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and direct programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For IL2RG (Source: Uniprot.org, NCBI)

Gene Name

IL2RG

Full Name

Cytokine receptor common subunit gamma

Weight

42.287kDa

Superfamily

type I cytokine receptor family

Alternative Names

CD132 antigen; CD132; CIDX; combined immunodeficiency, X-linked; common cytokine receptor gamma chain; Common gamma Chain; common gamma-chain; cytokine receptor common subunit gamma; gamma(c); IL-2 R gamma; IL-2 receptor subunit gamma; IL2R gamma; IL-2R subunit gamma; IL2RG; IL-2RG; IMD4; interleukin 2 receptor, gamma; Interleukin-2 receptor subunit gamma; P64; SCIDX; SCIDX1; severe combined immunodeficiency IL2RG CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1 interleukin 2 receptor subunit gamma cytokine receptor common subunit gamma|CD132 antigen|IL-2 receptor subunit gamma|IL-2R subunit gamma|common cytokine receptor gamma chain|gammaC|interleukin 2 receptor, gamma|nonfunctional common cytokine receptor gamma chain

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on IL2RG, check out the IL2RG Infographic

IL2RG infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IL2RG: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00308-1

100μg

$370
A00308-1-10ug

10μg sample (liquid)

$99
A00308-1-Biotin

100 μg Biotin conjugated

$570
A00308-1-Cy3

100 μg Cy3 conjugated

$570
A00308-1-Dylight488

100 μg Dylight488 conjugated

$570
A00308-1-Dylight550

100 μg Dylight550 conjugated

$570
A00308-1-Dylight594

100 μg Dylight594 conjugated

$570
A00308-1-FITC

100 μg FITC conjugated

$570
A00308-1-HRP

100 μg HRP conjugated

$570
A00308-1-APC

100 μg APC conjugated

$670
A00308-1-PE

100 μg PE conjugated

$670
A00308-1-carrier-free

Carrier Free

$370

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A00308-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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