Anti-IL28RA Antibody (Center)

Product Name

Anti-IL28RA Antibody (Center)

View all IL-28R alpha/IFN-lambda R1 Antibodies

SKU/Catalog Number

M05986

Size

80 µl

Description

Boster Bio Anti-IL28RA Antibody (Center) (Catalog # M05986). Tested in WB application(s). This antibody reacts with Human.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-IL28RA Antibody (Center) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M05986)

Host

Rabbit

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Polyclonal

Clone Number

1496CT356.164.25.226

Isotype

Rabbit IgG

Immunogen

This IL28RA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 387-420 amino acids from the Central region of human IL28RA.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M05986 is reactive to IFNLR1 in Human

Applications

M05986 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

57.653kDa

Background of IL-28R alpha/IFN-lambda R1

The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus- activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:2000

Validation Images & Assay Conditions

Click image to see more details

Anti-IL28RA Antibody (Center)at 1:2000 dilution + Ramos whole cell lysates
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution
Predicted band size : 58 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.

Gene/Protein Information For IFNLR1 (Source: Uniprot.org, NCBI)

Alternative Names

class II cytokine receptor CRF2/12; CRF2/12; CRF2-12; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; IFN-lambda R1; IFN-lambda receptor 1; IFN-lambda-R1; IFNLR; IFNLR1; IL-28 R alpha; IL-28 receptor subunit alpha; IL28R alpha; IL-28R1; IL28RA; IL-28Ra; IL-28R-alpha; Interferon lambda receptor 1; interferon lambda, receptor 1; interleukin 28 receptor A; interleukin 28 receptor, alpha (interferon, lambda receptor); interleukin 28 receptor, alpha; interleukin or cytokine receptor 2; interleukin-28 receptor subunit alpha; LICR2; Likely interleukin or cytokine receptor IFNLR1 CRF2/12, IFNLR, IL-28R1, IL28RA, LICR2 interferon lambda receptor 1 interferon lambda receptor 1|CRF2-12|IFN-lambda receptor 1|IFN-lambda-R1|IL-28 receptor subunit alpha|IL-28R-alpha|IL-28RA|class II cytokine receptor CRF2/12|cytokine receptor class-II member 12|cytokine receptor family 2 member 12|interleukin 28 alpha receptor|interleukin 28 receptor A|interleukin 28 receptor, alpha (interferon, lambda receptor)|interleukin or cytokine receptor 2|interleukin-28 receptor subunit alpha|likely interleukin or cytokine receptor 2

For more info on IFNLR1, check out the IFNLR1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IFNLR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the IFNLR1 Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis