Product Info Summary
SKU: | A01776-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | Flow Cytometry, WB |
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Product info
Product Name
Anti-Importin subunit alpha-1 KPNA2 Antibody
View all Importin alpha 2/KPNA2 Antibodies
SKU/Catalog Number
A01776-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Importin subunit alpha-1 KPNA2 Antibody catalog # A01776-2. Tested in WB,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Importin subunit alpha-1 KPNA2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01776-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human TRalpha
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01776-2 is reactive to KPNA2 in Human, Mouse, Rat
Applications
A01776-2 is guaranteed for Flow Cytometry, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.862kDa
Background of Importin alpha 2/KPNA2
Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
Quaderi N.A., Nat. Genet. 17:285-291(1997).
Perry J., Hum. Mol. Genet. 7:299-305(1998).
Van den Veyver I.B., Genomics 51:251-261(1998).<
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2,000
FC: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Flow Cytometry validation of KPNA2 using Anti-Importin subunit alpha-1 KPNA2 Antibody (A01776-2).
Flow cytometric analysis of 293T cells with KPNA2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).Click image to see more details
Figure 1. Western blotting validation for Anti-Importin subunit alpha-1 KPNA2 Antibody A01776-2
Western blot analysis of KPNA2 on different cell lysates using anti-KPNA2 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For KPNA2 (Source: Uniprot.org, NCBI)
Gene Name
KPNA2
Full Name
Importin subunit alpha-1
Weight
57.862kDa
Superfamily
importin alpha family
Alternative Names
Importin alpha 1; Importin alpha 2; importin-alpha-P1; IPOA1; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); Karyopherin subunit alpha-2; KPNA2; Pendulin; QIP2; QIP2importin alpha 2; RAG cohort 1; RAG cohort protein 1; RCH1; RCH1importin subunit alpha-2; SRP1; SRP1alpha; SRP1-alpha KPNA2 IPOA1, QIP2, RCH1, SRP1-alpha, SRP1alpha karyopherin subunit alpha 2 importin subunit alpha-1|RAG cohort protein 1|importin subunit alpha-2|importin-alpha-P1|karyopherin alpha 2 (RAG cohort 1, importin alpha 1)|pendulin
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KPNA2, check out the KPNA2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KPNA2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Importin subunit alpha-1 KPNA2 Antibody (A01776-2)
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No publications found for A01776-2
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