Product Info Summary
SKU: | A00447Y1355 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Insulin Receptor (phospho-Y1355) INSR Antibody
SKU/Catalog Number
A00447Y1355
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Insulin Receptor (phospho-Y1355) INSR Antibody catalog # A00447Y1355. Tested in WB,IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Insulin Receptor (phospho-Y1355) INSR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00447Y1355)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Insulin R around the phosphorylation site of T1375.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00447Y1355 is reactive to INSR in Human
Applications
A00447Y1355 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
156.333kDa
Background of INSR
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of INSR using Anti-Insulin Receptor (phospho-Y1355) INSR Antibody (A00447Y1355).
Immunohistochemistry (IHC) analyzes of p-Insulin Receptor (Y1355) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.For more protocol information of IHC
Click image to see more details
Figure 1. Western blotting validation for Anti-Insulin Receptor (phospho-Y1355) INSR Antibody A00447Y1355
Western blot (WB) analysis of p-Insulin Receptor (Y1355) pAb at 1:500 dilutionLane1:H1792 whole cell lysate(40ug)
Lane2:HepG2 whole cell lysate(40ug)
Lane3:A549 whole cell lysate(40ug)
Lane4:L02 whole cell lysate(40ug)
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For INSR (Source: Uniprot.org, NCBI)
Gene Name
INSR
Full Name
Insulin receptor
Weight
156.333kDa
Superfamily
protein kinase superfamily
Alternative Names
CD220 antigen; CD220; EC 2.7.10; EC 2.7.10.1; HHF5; insulin receptor; IR INSR CD220, HHF5 insulin receptor insulin receptor|IR
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on INSR, check out the INSR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for INSR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Insulin Receptor (phospho-Y1355) INSR Antibody (A00447Y1355)
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No publications found for A00447Y1355
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