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Product Info Summary
| SKU: | A00445 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IP, IHC, WB |
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Product info
Product Name
Anti-ITRAF TANK Antibody
SKU/Catalog Number
A00445
Size
50 µl
Form
Liquid
Description
Boster Bio Anti-ITRAF TANK Antibody (Catalog# A00445). Tested in IP, IHC, WB application(s). This antibody reacts with Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-ITRAF TANK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00445)
Host
Rabbit
Contents
50 μl sera
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide of human ITRAF (amino acids 346-367 DPSDAPFPSLDSPGKAIRGPQQ)
Cross-reactivity
(ELISA)Recombinant canine CCL3 Weak
(ELISA)Recombinant equine CCL3 None
(ELISA)Recombinant mouse CCL3 None
(ELISA)Recombinant rabbit CCL3 None
Reactive Species
A00445 is reactive to TANK in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
47.8 kDa
Background of TANK
ARHGAP22 is a Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. It acts as a GTPase activator for RAC1 by converting it to an inactive GDP-bound state and also inhibits RAC1-dependent lamellipodia formation. It may also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter. Anti-ARHGAP22 [p Ser22] antibody is ideal for researchers interested in Diabetes Research, Lipid and Metabolism research.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00445 is guaranteed for IP, IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000-1:2000
IHC (paraffin): 1:1000-1:5000
IHC (frozen): Users should optimize
IP: 1:50-1:200
Validation Images & Assay Conditions
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Immunohistochemical analysis of TANK/I-TRAF1 expression in formalin-fixed, paraffin-embedded normal human colon using primary antibody dilution ratio of 1:2000. A-A3, low and high magnification images. Hematoxylin-eosin counterstain.
Specific Publications For Anti-ITRAF TANK Antibody (A00445)
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