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Product Info Summary
| SKU: | A09437 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-JAKMIP1 Antibody
SKU/Catalog Number
A09437
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-JAKMIP1 Antibody (Catalog # A09437). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
JAKMIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-JAKMIP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09437)
Host
Rabbit
Contents
JAKMIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1. The immunogen is located within amino acids 260 - 310 of JAKMIP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of JAKMIP1 are known to exist. JAKMIP1 antibody is predicted to not cross-react with JAKMIP2.
Reactive Species
A09437 is reactive to Jakmip1 in Human, Mouse, Rat
Applications
A09437 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
73.139kDa
Background of Jakmip1
JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
JAKMIP1 antibody can be used for detection of JAKMIP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of JAKMIP1 in rat brain tissue lysate with JAKMIP1 antibody at (A) 1 and (B) 2 μg/mL
Protein Target Info & Infographic
Gene/Protein Information For Jakmip1 (Source: Uniprot.org, NCBI)
Gene Name
Jakmip1
Full Name
Janus kinase and microtubule-interacting protein 1
Weight
73.139kDa
Superfamily
JAKMIP family
Alternative Names
FLJ31564; GABA-B receptor-binding protein; Gababrbp; JAMIP1Jak and microtubule interacting protein 1; janus kinase and microtubule interacting protein 1; marlin-1; MARLIN1janus kinase and microtubule-interacting protein 1; Multiple alpha-helices and RNA-linker protein 1; multiple coiled-coil GABABR1-binding protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Jakmip1, check out the Jakmip1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Jakmip1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-JAKMIP1 Antibody (A09437)
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