Anti-KCNK13 Antibody

Product Name

Anti-KCNK13 Antibody

View all KCNK13 Antibodies

SKU/Catalog Number

A14190

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-KCNK13 Antibody (Catalog # A14190). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

KCNK13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-KCNK13 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14190)

Host

Rabbit

Contents

KCNK13 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

KCNK13 antibody was raised against a 15 amino acid synthetic peptide near the center of human KCNK13. The immunogen is located within amino acids 150 - 200 of KCNK13.

Cross-reactivity

KCNK13 antibody is predicted to not cross-react with other KCNK protein family members.

Reactive Species

A14190 is reactive to KCNK13 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

45.4 kDa

Background of KCNK13

The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A14190 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

KCNK13 antibody can be used for detection of KCNK13 by Western blot at 0.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information KCNK13

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