Product Info Summary
SKU: | A14190 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-KCNK13 Antibody
SKU/Catalog Number
A14190
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-KCNK13 Antibody (Catalog # A14190). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
KCNK13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-KCNK13 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14190)
Host
Rabbit
Contents
KCNK13 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
SK7
Isotype
IgG
Immunogen
KCNK13 antibody was raised against a 15 amino acid synthetic peptide near the center of human KCNK13. The immunogen is located within amino acids 150 - 200 of KCNK13.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
KCNK13 antibody is predicted to not cross-react with other KCNK protein family members.
Reactive Species
A14190 is reactive to KCNK13 in Human, Mouse, Rat
Applications
A14190 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
45.391kDa
Background of KCNK13
The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KCNK13 antibody can be used for detection of KCNK13 by Western blot at 0.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KCNK13 in rat brain tissue lysate with KCNK13 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of KCNK13 in human brain tissue with KCNK13 antibody at 5 μg/mL.
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Immunofluorescence of KCNK13 in human brain tissue with KCNK13 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For KCNK13 (Source: Uniprot.org, NCBI)
Gene Name
KCNK13
Full Name
Potassium channel subfamily K member 13
Weight
45.391kDa
Superfamily
two pore domain potassium channel (TC 1.A.1.8) family
Alternative Names
K2p13.1; potassium channel subfamily K member 13; potassium channel, subfamily K, member 13; tandem pore domain potassium channel THIK-1; THIK-1 KCNK13 K2p13.1, THIK-1, THIK1 potassium two pore domain channel subfamily K member 13 potassium channel subfamily K member 13|K2P13.1 potassium channel|potassium channel, subfamily K, member 13|potassium channel, two pore domain subfamily K, member 13|tandem pore domain halothane-inhibited potassium channel 1|tandem pore domain potassium channel THIK-1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCNK13, check out the KCNK13 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCNK13: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KCNK13 Antibody (A14190)
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No publications found for A14190
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