Product Info Summary
SKU: | A02648 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-KCNK3 Antibody
SKU/Catalog Number
A02648
Size
100ul
Form
Liquid
Description
Boster Bio Anti-KCNK3 Antibody catalog # A02648. Tested in WB,IHC applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-KCNK3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02648)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CAC1G protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02648 is reactive to KCNK3 in Human, Mouse
Applications
A02648 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
43.518kDa
Background of KCNK3
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
Ota T., Nat. Genet. 36:40-45(2004).
Sbrissa D., J. Biol. Chem. 277:6073-6079(2002).
Brill L.M., Anal. Chem. 76:2763-2772(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-KCNK3 Antibody A02648
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For KCNK3 (Source: Uniprot.org, NCBI)
Gene Name
KCNK3
Full Name
Potassium channel subfamily K member 3
Weight
43.518kDa
Superfamily
two pore domain potassium channel (TC 1.A.1.8) family
Alternative Names
Acid-sensitive potassium channel protein TASK-1; cardiac potassium channel; K2p3.1; OAT1; potassium channel subfamily K member 3; potassium channel, subfamily K, member 3; potassium inwardly-rectifying channel, subfamily K, member 3; TASK1; TASK-1; TASKacid-sensitive potassium channel protein TASK; TBAK1; TWIK-related acid-sensitive K(+) channel 1; TWIK-related acid-sensitive K+ channel; two P domain potassium channel; Two pore K(+) channel KT3.1; Two pore potassium channel KT3.1 KCNK3 K2p3.1, OAT1, PPH4, TASK, TASK-1, TASK1, TBAK1 potassium two pore domain channel subfamily K member 3 potassium channel subfamily K member 3|TWIK-related acid-sensitive K(+) channel 1|TWIK-related acid-sensitive K+ 1|TWIK-related acid-sensitive K+ channel|acid-sensitive potassium channel protein TASK|acid-sensitive potassium channel protein TASK-1|cardiac potassium channel|potassium channel, two pore domain subfamily K, member 3|potassium inwardly-rectifying channel, subfamily K, member 3|two P domain potassium channel|two pore K(+) channel KT3.1|two pore potassium channel KT3.1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCNK3, check out the KCNK3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCNK3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KCNK3 Antibody (A02648)
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No publications found for A02648
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