Product Info Summary
SKU: | A03659-1 |
---|---|
Size: | 100μl |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-KCNQ4/Kv7.4 Antibody
SKU/Catalog Number
A03659-1
Size
100μl
Form
Liquid
Description
Boster Bio Anti-KCNQ4/Kv7.4 Antibody catalog # A03659-1. Tested in WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-KCNQ4/Kv7.4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03659-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
5A6
Isotype
IgG
Immunogen
Synthesized peptide derived from the C-terminal region of human KCNQ4. at AA rangle: 620-700
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A03659-1 is reactive to KCNQ4 in Human, Mouse
Applications
A03659-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
77.101kDa
Background of Kv7.4
CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Western Blot (WB) analysis of specific cells using KCNQ4 Polyclonal antibody.
Protein Target Info & Infographic
Gene/Protein Information For KCNQ4 (Source: Uniprot.org, NCBI)
Gene Name
KCNQ4
Full Name
Potassium voltage-gated channel subfamily KQT member 4
Weight
77.101kDa
Superfamily
potassium channel family
Alternative Names
DFNA2; DFNA2A; KQT-like 4; Kv7.4; potassium channel KQT-like 4; Potassium channel subunit alpha KvLQT4; potassium voltage-gated channel subfamily KQT member 4; potassium voltage-gated channel, KQT-like subfamily, member 4; Voltage-gated potassium channel subunit Kv7.4 KCNQ4 DFNA2, DFNA2A, KV7.4 potassium voltage-gated channel subfamily Q member 4 potassium voltage-gated channel subfamily KQT member 4|potassium channel KQT-like 4|potassium channel subunit alpha KvLQT4|potassium channel, voltage gated KQT-like subfamily Q, member 4|potassium voltage-gated channel, KQT-like subfamily, member 4
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCNQ4, check out the KCNQ4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCNQ4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KCNQ4/Kv7.4 Antibody (A03659-1)
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No publications found for A03659-1
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Customer Reviews
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Customer Q&As
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5 Customer Q&As for Anti-KCNQ4/Kv7.4 Antibody
Question
I have attached the WB image, lot number and protocol we used for pigmented layer of retina using anti-KCNQ4/Kv7.4 antibody A03659-1. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2020-01-14
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2020-01-14
Question
We are currently using anti-KCNQ4/Kv7.4 antibody A03659-1 for human tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, mouse. Is it true that the antibody can work on pig tissues as well?
Verified Customer
Verified customer
Asked: 2019-09-09
Answer
The anti-KCNQ4/Kv7.4 antibody (A03659-1) has not been tested for cross reactivity specifically with pig tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-09-09
Question
Will anti-KCNQ4/Kv7.4 antibody A03659-1 work for WB with pigmented layer of retina?
Verified Customer
Verified customer
Asked: 2019-05-16
Answer
According to the expression profile of pigmented layer of retina, KCNQ4 is highly expressed in pigmented layer of retina. So, it is likely that anti-KCNQ4/Kv7.4 antibody A03659-1 will work for WB with pigmented layer of retina.
Boster Scientific Support
Answered: 2019-05-16
Question
I would like to test anti-KCNQ4/Kv7.4 antibody A03659-1 on human pigmented layer of retina for research purposes, then I may be interested in using anti-KCNQ4/Kv7.4 antibody A03659-1 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2017-06-05
Answer
The products we sell, including anti-KCNQ4/Kv7.4 antibody A03659-1, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2017-06-05
Question
I was wanting to use your anti-KCNQ4/Kv7.4 antibody for WB for human pigmented layer of retina on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human pigmented layer of retina identification?
R. Krishna
Verified customer
Asked: 2014-06-06
Answer
It shows on the product datasheet, A03659-1 anti-KCNQ4/Kv7.4 antibody has been validated for WB on human, mouse tissues. We have an innovator award program that if you test this antibody and show it works in human pigmented layer of retina in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2014-06-06