Anti-KCNQ4/Kv7.4 Antibody

Kv7.4 antibody

Boster Bio Anti-KCNQ4/Kv7.4 Antibody catalog # A03659-1. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A03659-1
Size: 100μl
Reactive Species: Human, Mouse
Host: Rabbit
Application: WB

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Product Name

Anti-KCNQ4/Kv7.4 Antibody

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SKU/Catalog Number

A03659-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-KCNQ4/Kv7.4 Antibody catalog # A03659-1. Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-KCNQ4/Kv7.4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03659-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

5A6

Isotype

IgG

Immunogen

Synthesized peptide derived from the C-terminal region of human KCNQ4. at AA rangle: 620-700

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03659-1 is reactive to KCNQ4 in Human, Mouse

Applications

A03659-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

77.101kDa

Background of Kv7.4

CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

Gene/Protein Information For KCNQ4 (Source: Uniprot.org, NCBI)

Gene Name

KCNQ4

Full Name

Potassium voltage-gated channel subfamily KQT member 4

Weight

77.101kDa

Superfamily

potassium channel family

Alternative Names

DFNA2; DFNA2A; KQT-like 4; Kv7.4; potassium channel KQT-like 4; Potassium channel subunit alpha KvLQT4; potassium voltage-gated channel subfamily KQT member 4; potassium voltage-gated channel, KQT-like subfamily, member 4; Voltage-gated potassium channel subunit Kv7.4 KCNQ4 DFNA2, DFNA2A, KV7.4 potassium voltage-gated channel subfamily Q member 4 potassium voltage-gated channel subfamily KQT member 4|potassium channel KQT-like 4|potassium channel subunit alpha KvLQT4|potassium channel, voltage gated KQT-like subfamily Q, member 4|potassium voltage-gated channel, KQT-like subfamily, member 4

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on KCNQ4, check out the KCNQ4 Infographic

KCNQ4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for KCNQ4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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5 Customer Q&As for Anti-KCNQ4/Kv7.4 Antibody

Question

I have attached the WB image, lot number and protocol we used for pigmented layer of retina using anti-KCNQ4/Kv7.4 antibody A03659-1. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2020-01-14

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2020-01-14

Question

We are currently using anti-KCNQ4/Kv7.4 antibody A03659-1 for human tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, mouse. Is it true that the antibody can work on pig tissues as well?

Verified Customer

Verified customer

Asked: 2019-09-09

Answer

The anti-KCNQ4/Kv7.4 antibody (A03659-1) has not been tested for cross reactivity specifically with pig tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-09-09

Question

Will anti-KCNQ4/Kv7.4 antibody A03659-1 work for WB with pigmented layer of retina?

Verified Customer

Verified customer

Asked: 2019-05-16

Answer

According to the expression profile of pigmented layer of retina, KCNQ4 is highly expressed in pigmented layer of retina. So, it is likely that anti-KCNQ4/Kv7.4 antibody A03659-1 will work for WB with pigmented layer of retina.

Boster Scientific Support

Answered: 2019-05-16

Question

I would like to test anti-KCNQ4/Kv7.4 antibody A03659-1 on human pigmented layer of retina for research purposes, then I may be interested in using anti-KCNQ4/Kv7.4 antibody A03659-1 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2017-06-05

Answer

The products we sell, including anti-KCNQ4/Kv7.4 antibody A03659-1, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2017-06-05

Question

I was wanting to use your anti-KCNQ4/Kv7.4 antibody for WB for human pigmented layer of retina on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human pigmented layer of retina identification?

R. Krishna

Verified customer

Asked: 2014-06-06

Answer

It shows on the product datasheet, A03659-1 anti-KCNQ4/Kv7.4 antibody has been validated for WB on human, mouse tissues. We have an innovator award program that if you test this antibody and show it works in human pigmented layer of retina in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2014-06-06

Order DetailsPrice
A03659-1

100uL

$399

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