Anti-KLHL21 Monoclonal Antibody

Product Name

Anti-KLHL21 Monoclonal Antibody

View all Kelch-Like Family Member 21 Antibodies

SKU/Catalog Number

A12797

Size

100μl

Form

Liquid

Description

Boster Bio Anti-KLHL21 Monoclonal Antibody catalog # A12797. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-KLHL21 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12797)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

2H4

Isotype

IgG

Immunogen

Purified recombinant fragment of human KLHL21 expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12797 is reactive to KLHL21 in Human

Applications

A12797 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

66.617kDa

Background of Kelch-Like Family Member 21

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Innovating Scientists Reward

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000
IHC, 1:200-1:1000

Validation Images & Assay Conditions

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Western Blot (WB) analysis using KLHL21 Monoclonal antibody against recombinant KLHL21 protein (1).

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Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain tissues with DAB staining using KLHL21 Monoclonal antibody.

Gene/Protein Information For KLHL21 (Source: Uniprot.org, NCBI)

Alternative Names

kelch-like 21 (Drosophila); Kelch-Like Protein 21; KIAA0469; KLHL21 KLHL21 kelch like family member 21 kelch-like protein 21

For more info on KLHL21, check out the KLHL21 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for KLHL21: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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