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LAG3 antibody (M02869-1) performs well in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB and shows reactivity with Human.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Flow cytometry analysis of LAG-3 over expressing HEK293 cells using LAG-3 antibody at 1 μg/ml. Blue: untransfected HEK293 cells. Yellow: LAG-3 over expressing HEK293 cells.
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Anti-LAG3 Monoclonal Antibody [2G8]
LAG3 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human | Mouse | ELISA, Flow Cytometry, IF, IHC-P, ICC, WB |
Recommend Dilution
Application
Dilution
Species
LAG-3 antibody can be used for ELISA starting at 0.25 μg/mL. For Western blot start at 0.25 μg/mL. For Immunocytochemistry start at 1 μg/mL. For Immunofluorescence start at 10 μg/mL. For Immunohistochemistry start at 5 μg/mL. For Flow Cytometry start at 1 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples; Immunocytochemistry in human samples; Immunofluorescence in human samples and Flow Cytometry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-LAG3 Monoclonal Antibody [2G8]
View all LAG3 Antibodies
View all LAG3 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
LAG-3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Mouse
Contents
LAG-3 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol.
Clonality
Monoclonal
Clone Number
Clone: 2G8
Isotype
IgG1,k
Immunogen
LAG-3 antibody was raised against the extracellular domain of human LAG-3
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
57.4 kDa
Background of LAG3
The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy.
Cite This Product
Anti-LAG3 Monoclonal Antibody [2G8] (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02869-1)
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Product Promise
We promise Anti-LAG3 Monoclonal Antibody [2G8] performs excellently in relevant applications for ELISA, Flow Cytometry, IF, IHC-P, ICC, WB. If it doesn't perform as promised, we will refund the product. Learn more
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M02869-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 10, 2026