Anti-Lamin B1 LMNB1 Rabbit Monoclonal Antibody

Lamin B1 antibody

Boster Bio Anti-Lamin B1 LMNB1 Rabbit Monoclonal Antibody catalog # M02778. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat. Cited in 10 publication(s).

Product Info Summary

SKU: M02778
Size: 100 μl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IP, IF, IHC, ICC, WB

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Product Name

Anti-Lamin B1 LMNB1 Rabbit Monoclonal Antibody

View all Lamin B1 Antibodies

SKU/Catalog Number

M02778

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-Lamin B1 LMNB1 Rabbit Monoclonal Antibody catalog # M02778. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Lamin B1 LMNB1 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02778)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

DC-12

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human Lamin B1

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Detects ~20kDa. Does not cross-react with αB-crystallin, βL-crystallin, ΒH- crystallin, γ-crystallin, HSP25, HSP27 or HSP47 proteins.

Reactive Species

M02778 is reactive to LMNB1 in Human, Mouse, Rat

Applications

M02778 is guaranteed for IP, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

70 kDa, 90 kDa

Calculated molecular weight

66.408kDa

Background of Lamin B1

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:3000-1:10000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50

Validation Images & Assay Conditions

Gene/Protein Information For LMNB1 (Source: Uniprot.org, NCBI)

Gene Name

LMNB1

Full Name

Lamin-B1

Weight

66.408kDa

Superfamily

intermediate filament family

Alternative Names

ADLD; Lamin B1; lamin-B1; LMN; LMN2; LMNB; LMNB1; MGC111419 LMNB1 ADLD, LMN, LMN2, LMNB, MCPH26 lamin B1 lamin-B1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on LMNB1, check out the LMNB1 Infographic

LMNB1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for LMNB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

M02778 has been cited in 10 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Li JS,Fan LY,Yuan MD,Xing MY.Salidroside Inhibits Lipopolysaccharide-ethanol-induced Activation of Proinflammatory Macrophages via Notch Signaling Pathway.Curr Med Sci.2019 Aug;39(4):526-533.doi:10.1007/s11596-019-2069-4.Epub 2019 Jul 25.PMID:31346986.
Species: Human
M02778 usage in article: APP:WB, SAMPLE:THP-1 CELL, DILUTION:NA

Na,L.,Q,B.,Xiumei,Z.et al.Research into the intervention effect of folic acid on arsenic-induced heart abnormalities in fetal rats during the periconception period.BMC Cardiovasc Disord 20, 139 (2020).https://doi.org/10.1186/s12872-020-01418-z
Species: Rat
M02778 usage in article: APP:WB, SAMPLE:HEART TISSUE, DILUTION:NA

Zhang B,Zhong Q,Chen X,Wu X,Sha R,Song G,Zhang C,Chen X.Neuroprotective Effects of Celastrol on Transient Global Cerebral Ischemia Rats via Regulating HMGB1/NF-κB Signaling Pathway.Front Neurosci.2020 Aug 11;14:847.doi:10.3389/fnins.2020.00847.PMID:328485
Species: Rat
M02778 usage in article: APP:WB, SAMPLE:HIPPOCAMPUL TISSUE, DILUTION:1:500

Zhong J,Ye S,Zhou X,Huang J,Li X,Zhang S,Zhou J,Chen D,Li C.Plastrum Testudinis Extracts Promote NSC Differentiation into Dopaminergic Neuron by Regulating the Interaction of TET1 and FoxA2.Evid Based Complement Alternat Med.2020 Apr 20;2020:9104135.doi:1
Species: Rat
M02778 usage in article: APP:WB, SAMPLE:BRAIN TISSUE, DILUTION:1:100

Xu X,Zhou Y,Fu B,Zhang J,Dong Z,Zhang X,Shen N,Sun R,Tian Z,Wei H. PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter. FASEB J.2020 May;34(5):6479-6492. doi: 10.1096/fj. 202000121R.Epub 2020 Mar 19. PMID:32190943.
Species: Mouse
M02778 usage in article: APP:WB, SAMPLE:293T CELL, DILUTION:NA

Li X,Shi MQ,Chen C,Du JR.Phthalide derivative CD21 ameliorates ischemic brain injury in a mouse model of global cerebral ischemia: involvement of inhibition of NLRP3.Int Immunopharmacol.2020 Sep;86:106714.doi: 10.1016/j.intimp.2020.106714.Epub 2020 Jun 24
Species: Mouse
M02778 usage in article: APP:WB, SAMPLE:BRAIN TISSUE, DILUTION:1:250

Overexpression of DJ-1 reduces oxidativestressand attenuates hypoxia/reoxygenation injury in NRK-52Ecellsexposed to high glucose

Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart

Clinicopathologic and prognostic significance of p21 (Cip1/Waf1) expression in bladder cancer.

Simulated microgravity inhibits osteogenic differentiation of mesenchymal stem?cells?via depolymerizing F-actin to impede TAZ nuclear translocation

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Order DetailsPrice
M02778

100μL

$370
M02778-30ul

30μL sample

$99
M02778-carrier-free

Carrier Free

$370

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