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Product Info Summary
| SKU: | A08888 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-LMCD1 Antibody (C-term)
SKU/Catalog Number
A08888
Size
80 µl
Description
Boster Bio Anti-LMCD1 Antibody (C-term) (Catalog # A08888). Tested in WB application(s). This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-LMCD1 Antibody (C-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08888)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.
Reactive Species
A08888 is reactive to LMCD1 in Human, Mouse, Rat
Calculated molecular weight
40.8 kDa
Background of LMCD1
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08888 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
Validation Images & Assay Conditions
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Western blot analysis of lysates from human skeletal muscle, mouse lung, rat lung tissue lysate (from left to right), using LMCD1 Antibody (C-term). A08888 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
Specific Publications For Anti-LMCD1 Antibody (C-term) (A08888)
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