Anti-LRRC32 Antibody (Monoclonal, Plato-1), PE Conjugated

Product Name

Anti-LRRC32 Antibody (Monoclonal, Plato-1), PE Conjugated

View all LRRC32/GARP Antibodies

SKU/Catalog Number

E08199

Size

100μg/vial

Form

Liquid

Description

Boster Bio Anti-LRRC32 Antibody (Monoclonal, Plato-1), PE Conjugated catalog # E08199. Tested in Flow Cytometry applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store vial at 4°C prior to restoration. Restore with 0.1 mL of deionized water (or equivalent). For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Cite This Product

Anti-LRRC32 Antibody (Monoclonal, Plato-1), PE Conjugated (Boster Biological Technology, Pleasanton CA, USA, Catalog # E08199)

Host

Mouse

Contents

Each vial contains 0.09% sodium azide.

Clonality

Monoclonal

Clone Number

Plato-1

Isotype

IgG1

Immunogen

Recombinant human LRRC32 (aa 20-627).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

E08199 is reactive to LRRC32 in Human, Mouse

Applications

E08199 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

71.979kDa

Background of LRRC32/GARP

Anti-IL17E recognizes IL-17E (also known as IL25). IL-17E is produced and secreted by intra-epithelial lymphocytes, lung epithelial cells, alveolar macrophages, eosinophils, basophils, NKT cells, mast cells and cells of the gastro-intestinal tract and uterus. IL-17E stimulates the production of Th2-type cytokines. IL-17E limits Th17 cell development by inducing the expression of IL-13 by dendritic cells or by inhibiting IL-23 production by macrophages. Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. A number of cytokines, including IL-17E, have been implicated as oncogenes, reflecting the importance of these proteins in cell growth and survival. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and pro-inflammatory pathologies.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry, 1:100, Human, Mouse

Validation Images & Assay Conditions

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Flow cytometry analysis, intracellular stained, of 10⁶ Jurkat cells using LRRC32, mAb (Plato-1) (PE conjugate) at a concentration of 10μg/ml.

Gene/Protein Information For LRRC32 (Source: Uniprot.org, NCBI)

Alternative Names

D11S833E; D11S833Eleucine-rich repeat-containing protein 32; GARP; GARPGarpin; Garpin; Glycoprotein A repetitions predominantgarpin; leucine rich repeat containing 32; LRRC32 LRRC32 CPPRDD, D11S833E, GARP leucine rich repeat containing 32 transforming growth factor beta activator LRRC32|garpin|glycoprotein A repetitions predominant|leucine-rich repeat-containing protein 32

For more info on LRRC32, check out the LRRC32 Infographic

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In this infographic, you will see the following information for LRRC32: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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