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Product Info Summary
| SKU: | A10157 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Lymphocyte antigen 6K LY6K Antibody
SKU/Catalog Number
A10157
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Lymphocyte antigen 6K LY6K Antibody (Catalog # A10157). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
LY6K antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Lymphocyte antigen 6K LY6K Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10157)
Host
Rabbit
Contents
LY6K Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
LY6K antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human LY6K. The immunogen is located within the first 50 amino acids of LY6K.
Cross-reactivity
Multiple isoforms of LY6K are known to exist.
Reactive Species
A10157 is reactive to LY6K in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
18.7 kDa
Background of LY6K
The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A10157 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
LY6K antibody can be used for detection of LY6K by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of LY6K in HeLa cell lysate with LY6K antibody at (A) 1 and (B) 2 μg/mL.
Specific Publications For Anti-Lymphocyte antigen 6K LY6K Antibody (A10157)
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