Anti-mAChR M5 Antibody

Product Name

Anti-mAChR M5 Antibody

View all Muscarinic Acetylcholine Receptor M5/CHRM5 Antibodies

SKU/Catalog Number

A12171

Size

100μl

Form

Liquid

Description

Boster Bio Anti-mAChR M5 Antibody catalog # A12171. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-mAChR M5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12171)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

F7E4

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human mAChR M5. at AA rangle: 260-340

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12171 is reactive to CHRM5 in Human

Applications

A12171 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

60.074kDa

Background of Muscarinic Acetylcholine Receptor M5/CHRM5

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

Click image to see more details

Western Blot (WB) analysis of Jurkat cells using mAChR M5 Polyclonal antibody.

Gene/Protein Information For CHRM5 (Source: Uniprot.org, NCBI)

Alternative Names

cholinergic receptor, muscarinic 5; CHRM5; HM5; M5; M5R; mAChR M5; MGC41838; muscarinic acetylcholine receptor M5 CHRM5 HM5 cholinergic receptor muscarinic 5 muscarinic acetylcholine receptor M5|acetylcholine receptor, muscarinic 5

For more info on CHRM5, check out the CHRM5 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CHRM5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the CHRM5 Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis