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Product Info Summary
| SKU: | A06134 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-MAP4K6 MINK1 Antibody
SKU/Catalog Number
A06134
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-MAP4K6 MINK1 Antibody (Catalog # A06134). Tested in WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MAP4K6 MINK1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06134)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human MAP4K6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06134 is reactive to MINK1 in Human, Mouse
Applications
A06134 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
149.822kDa
Background of MAP4K6
Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
Dan I., FEBS Lett. 469:19-23(2000).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Olsen J.V., Cell 127:635-648(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
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Western blot analysis of extracts from COLO cells, using MAP4K6 antibody A06134.
Protein Target Info & Infographic
Gene/Protein Information For MINK1 (Source: Uniprot.org, NCBI)
Gene Name
MINK1
Full Name
Misshapen-like kinase 1
Weight
149.822kDa
Superfamily
protein kinase superfamily
Alternative Names
B55; EC 2.7.11; GCK family kinase MiNK; hMINK; hMINKbeta; MAP4K6EC 2.7.11.1; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MGC21111; MINKMEKKK 6; Misshapen/NIK-related kinase; misshapen-like kinase 1 (zebrafish); misshapen-like kinase 1; Mitogen-activated protein kinase kinase kinase kinase 6; serine/threonine protein kinase; YSK2; ZC3 MINK1 B55, MAP4K6, MINK, YSK2, ZC3 misshapen like kinase 1 misshapen-like kinase 1|GCK family kinase MINK|MAPK/ERK kinase kinase kinase 6|MEK kinase kinase 6|MEKKK 6|misshapen/NIK-related kinase|mitogen-activated protein kinase kinase kinase kinase 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MINK1, check out the MINK1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MINK1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MAP4K6 MINK1 Antibody (A06134)
Hello CJ!
No publications found for A06134
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