Product Info Summary
SKU: | A14279-1 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-MettL7A Antibody
SKU/Catalog Number
A14279-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MettL7A Antibody (Catalog # A14279-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
MettL7A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MettL7A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14279-1)
Host
Rabbit
Contents
MettL7A Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MettL7A antibody was raised against a 13 amino acid synthetic peptide near the center of human MettL7A. The immunogen is located within amino acids 130 - 180 of MettL7A.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of MettL7A are known to exist. This antibody is predicted to not cross-react with MettL7B.
Reactive Species
A14279-1 is reactive to METTL7A in Human, Mouse
Applications
A14279-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
28.319kDa
Background of METTL7A
MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MettL7A antibody can be used for detection of MettL7A by Western blot at 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 2 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of MettL7A in MCF cell lysate with MettL7A antibody at 2 μg/mL.
Click image to see more details
Immunocytochemistry of MettL7a in MCF7 cells with MettL7a antibody at 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For METTL7A (Source: Uniprot.org, NCBI)
Gene Name
METTL7A
Full Name
Methyltransferase-like protein 7A
Weight
28.319kDa
Superfamily
methyltransferase superfamily
Alternative Names
Methyltransferase-like protein 7A METTL7A AAM-B, AAMB methyltransferase like 7A methyltransferase-like protein 7A|protein AAM-B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on METTL7A, check out the METTL7A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for METTL7A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MettL7A Antibody (A14279-1)
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No publications found for A14279-1
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Customer Reviews
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