Anti-MICOS complex subunit MIC25 CHCHD6 Antibody

Chchd6 antibody

Boster Bio Anti-MICOS complex subunit MIC25 CHCHD6 Antibody (Catalog # A09965). Tested in ELISA, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A09965
Size: 0.1 mg
Reactive Species: Human
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-MICOS complex subunit MIC25 CHCHD6 Antibody

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SKU/Catalog Number

A09965

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-MICOS complex subunit MIC25 CHCHD6 Antibody (Catalog # A09965). Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

CHCHD6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-MICOS complex subunit MIC25 CHCHD6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09965)

Host

Rabbit

Contents

CHCHD6 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

Rabbit polyclonal CHCHD6 antibody was raised against a 17 amino acid peptide near the amino terminus of human CHCHD6. The immunogen is located within amino acids 20 - 70 of CHCHD6.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

CHCHD6 is predicted to not cross-react to other members of the CHCHD family.

Reactive Species

A09965 is reactive to Chchd6 in Human

Applications

A09965 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

29.852kDa

Background of Chchd6

CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CHCHD6 antibody can be used for detection of CHCHD6 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For Chchd6 (Source: Uniprot.org, NCBI)

Gene Name

Chchd6

Full Name

MICOS complex subunit Mic25

Weight

29.852kDa

Superfamily

MICOS complex subunit Mic19 family

Alternative Names

coiled-coil-helix-coiled-coil-helix domain containing 6; coiled-coil-helix-coiled-coil-helix domain-containing protein 6; MGC13016

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Chchd6, check out the Chchd6 Infographic

Chchd6 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Chchd6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A09965-0.1 mg

0.1 mg

$449

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