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Product Info Summary
| SKU: | A08709 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-MLX-interacting protein MLXIP Antibody
SKU/Catalog Number
A08709
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MLX-interacting protein MLXIP Antibody (Catalog # A08709). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
MLXIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MLX-interacting protein MLXIP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08709)
Host
Rabbit
Contents
MLXIP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MLXIP antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human MLXIP.
Reactive Species
A08709 is reactive to MLXIP in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
101.2 kDa
Background of MLXIP
MLXIP is a member of the Myc superfamily of transcription factors and functions as part of a heterodimer with Max-like protein X (MLX) to activate transcription (1). MLXIP contributes to the regulation of glucose homeostasis as the MLXIP/MLX heterodimer activates expression of thioredoxin-interacting protein (TXNIP), a potent inhibitor of cellular glucose uptake and aerobic glycolysis. The mammalian target of rapamycin (mTOR) suppresses the activation of the TXNIP pathway by binding to MLXIP, thereby preventing the MLXIP/MLX heterodimer formation (2). MLXIP interaction with Myc may also be involved in metabolic reprogramming and tumorigenesis (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08709 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MLXIP antibody can be used for Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MLXIP in MCF7 cell lysate with MLXIP antibody at 1 μg/mL.
Specific Publications For Anti-MLX-interacting protein MLXIP Antibody (A08709)
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