Product Info Summary
SKU: | A06675-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-MNDA (V406) Antibody
SKU/Catalog Number
A06675-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-MNDA (V406) Antibody catalog # A06675-1. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MNDA (V406) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06675-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human MNDA.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A06675-1 is reactive to MNDA in Human, Mouse, Rat
Applications
A06675-1 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
45.836kDa
Background of MNDA
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.
Briggs J.A., J. Cell. Biochem. 49:82-92(1992).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Burrus G.R., J. Cell. Biochem. 48:190-202(1992).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of MNDA using Anti-MNDA (V406) Antibody (A06675-1).
Immunohistochemistry (IHC) analyzes of MNDA (V406) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibodyClick image to see more details
Figure 2. Immunohistochemistry validation of MNDA using Anti-MNDA (V406) Antibody (A06675-1).
Immunohistochemistry (IHC) analyzes of MNDA (V406) pAb in paraffin-embedded human kidney carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibodyProtein Target Info & Infographic
Gene/Protein Information For MNDA (Source: Uniprot.org, NCBI)
Gene Name
MNDA
Full Name
Myeloid cell nuclear differentiation antigen
Weight
45.836kDa
Alternative Names
myeloid cell nuclear differentiation antigen; PYHIN3 MNDA PYHIN3 myeloid cell nuclear differentiation antigen myeloid cell nuclear differentiation antigen|epididymis secretory sperm binding protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MNDA, check out the MNDA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MNDA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MNDA (V406) Antibody (A06675-1)
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No publications found for A06675-1
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Customer Reviews
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