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Product Info Summary
| SKU: | A03619 |
|---|---|
| Size: | 100μl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Mnk2 MKNK2 Antibody
SKU/Catalog Number
A03619
Size
100μl
Form
Liquid
Description
Boster Bio Anti-Mnk2 MKNK2 Antibody catalog # A03619. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Mnk2 MKNK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03619)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
5A6
Isotype
IgG
Immunogen
Synthesized peptide derived from the Internal region of human Mnk2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A03619 is reactive to MKNK2 in Human, Mouse, Rat
Applications
A03619 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
51.875kDa
Background of MNK2
CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
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Western Blot (WB) analysis of HeLa cells using Mnk2 Polyclonal antibody.
Protein Target Info & Infographic
Gene/Protein Information For MKNK2 (Source: Uniprot.org, NCBI)
Gene Name
MKNK2
Full Name
MAP kinase-interacting serine/threonine-protein kinase 2
Weight
51.875kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.11; EC 2.7.11.1; G protein-coupled receptor kinase 7; GPRK7Putative map kinase interacting kinase; MAP kinase interacting serine/threonine kinase 2; MAP kinase signal-integrating kinase 2; Mnk2; MNK2MAP kinase-interacting serine/threonine-protein kinase 2 MKNK2 GPRK7, MNK2 MAPK interacting serine/threonine kinase 2 MAP kinase-interacting serine/threonine-protein kinase 2|G protein-coupled receptor kinase 7|MAP kinase interacting serine/threonine kinase 2|MAP kinase signal-integrating kinase 2|MAPK signal-integrating kinase 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MKNK2, check out the MKNK2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MKNK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Mnk2 MKNK2 Antibody (A03619)
Hello CJ!
No publications found for A03619
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Recommended Resources
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Customer Reviews
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Customer Q&As
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Find answers in Q&As, reviews.
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6 Customer Q&As for Anti-Mnk2 MKNK2 Antibody
Question
My question regards to test anti-Mnk2 antibody A03619 on mouse cervix carcinoma for research purposes, then I may be interested in using anti-Mnk2 antibody A03619 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2020-04-16
Answer
The products we sell, including anti-Mnk2 antibody A03619, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2020-04-16
Question
My question regarding product A03619, anti-Mnk2 antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?
Verified Customer
Verified customer
Asked: 2020-04-02
Answer
We do not advise storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free A03619 anti-Mnk2 antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.
Boster Scientific Support
Answered: 2020-04-02
Question
Does anti-Mnk2 antibody A03619 work on goat WB with cervix carcinoma erythroleukemia?
Verified Customer
Verified customer
Asked: 2020-02-21
Answer
Our lab technicians have not validated anti-Mnk2 antibody A03619 on goat. You can run a BLAST between goat and the immunogen sequence of anti-Mnk2 antibody A03619 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated goat samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in goat cervix carcinoma erythroleukemia in WB, you can get your next antibody for free.
Boster Scientific Support
Answered: 2020-02-21
Question
We are currently using anti-Mnk2 antibody A03619 for mouse tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on dog tissues as well?
F. Banerjee
Verified customer
Asked: 2020-02-03
Answer
The anti-Mnk2 antibody (A03619) has not been validated for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2020-02-03
Question
Would anti-Mnk2 antibody A03619 work for WB with cervix carcinoma?
Verified Customer
Verified customer
Asked: 2019-02-13
Answer
According to the expression profile of cervix carcinoma, MKNK2 is highly expressed in cervix carcinoma. So, it is likely that anti-Mnk2 antibody A03619 will work for WB with cervix carcinoma.
Boster Scientific Support
Answered: 2019-02-13
Question
Is a blocking peptide available for product anti-Mnk2 antibody (A03619)?
G. Gonzalez
Verified customer
Asked: 2018-07-20
Answer
We do provide the blocking peptide for product anti-Mnk2 antibody (A03619). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2018-07-20
