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Product Info Summary
| SKU: | A30172 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-MORF4 Antibody
SKU/Catalog Number
A30172
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MORF4 Antibody (Catalog # A30172). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
MORF4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MORF4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30172)
Host
Rabbit
Contents
MORF4 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MORF4 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human MORF4. The immunogen is located within amino acids 20 - 70 of MORF4.
Reactive Species
A30172 is reactive to MORF4 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Background of MORF4
Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A30172 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Recommend Dilution
MORF4 antibody can be used for the detection of MORF4 by Western blot at 1 and 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MORF4 in K562 cell lysate with MORF4 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of MORF4 in human brain tissue with MORF4 antibody at 5 μg/mL.
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Immunofluorescence of MORF4 in HepG2 cells with MORF4 antibody at 20 μg/mL.
Specific Publications For Anti-MORF4 Antibody (A30172)
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