Anti-Na+ CP type Alpha-pan (E1476) SCN9A Antibody

Nav1.7 antibody

Boster Bio Anti-Na+ CP type Alpha-pan (E1476) SCN9A Antibody catalog # A00920-2. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A00920-2
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC

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Product Name

Anti-Na+ CP type Alpha-pan (E1476) SCN9A Antibody

View all Nav1.7 Antibodies

SKU/Catalog Number

A00920-2

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Na+ CP type Alpha-pan (E1476) SCN9A Antibody catalog # A00920-2. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Na+ CP type Alpha-pan (E1476) SCN9A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00920-2)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human ATF-2 around the phosphorylation site of T73.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00920-2 is reactive to SCN9A in Human, Mouse, Rat

Applications

A00920-2 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

226.372kDa

Background of Nav1.7

Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.

Gotoh I., J. Biol. Chem. 276:4276-4286(2001).
Bloem L.J., J. Mol. Cell. Cardiol. 33:1739-1750(2001).
Gross E.A., J. Biol. Chem. 277:13873-13882(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC: 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For SCN9A (Source: Uniprot.org, NCBI)

Gene Name

SCN9A

Full Name

Sodium channel protein type 9 subunit alpha

Weight

226.372kDa

Superfamily

sodium channel (TC 1.A.1.10) family

Alternative Names

ETHA; FEB3B; NE-NA; NENAVoltage-gated sodium channel subunit alpha Nav1.7; Neuroendocrine sodium channel; Peripheral sodium channel 1; PN1hNE-Na; sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; sodium channel, voltage-gated, type IX, alpha subunit; voltage-gated sodium channel alpha subunit Nav1.7; voltage-gated, type IX, alpha polypeptide SCN9A ETHA, FEB3B, GEFSP7, HSAN2D, NE-NA, NENA, Nav1.7, PN1, SFNP sodium voltage-gated channel alpha subunit 9 sodium channel protein type 9 subunit alpha|hNE-Na|neuroendocrine sodium channel|peripheral sodium channel 1|sodium channel protein type IX subunit alpha|sodium channel, voltage-gated, type IX, alpha polypeptide|sodium channel, voltage-gated, type IX, alpha subunit|voltage-gated sodium channel alpha subunit Nav1.7|voltage-gated sodium channel subunit alpha Nav1.7

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SCN9A, check out the SCN9A Infographic

SCN9A infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SCN9A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00920-2-100ul

100ul

$405

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