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Product Info Summary
| SKU: | A15112 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-NALP8 NLRP8 Antibody
SKU/Catalog Number
A15112
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-NALP8 NLRP8 Antibody (Catalog # A15112). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
NALP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-NALP8 NLRP8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15112)
Host
Rabbit
Contents
NALP8 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
NALP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP8. The immunogen is located within amino acids 130 - 180 of NALP8.
Reactive Species
A15112 is reactive to NLRP8 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
119.4 kDa
Background of NLRP8
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A15112 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
NALP8 antibody can be used for detection of NALP8 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of NALP8 in human colon tissue lysate with NALP8 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Specific Publications For Anti-NALP8 NLRP8 Antibody (A15112)
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