Anti-NEUCRIN DRAXIN Antibody

Draxin/C1orf187 antibody

Boster Bio Anti-NEUCRIN DRAXIN Antibody (Catalog # A09941). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A09941
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-NEUCRIN DRAXIN Antibody

View all Draxin/C1orf187 Antibodies

SKU/Catalog Number

A09941

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-NEUCRIN DRAXIN Antibody (Catalog # A09941). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

NEUCRIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-NEUCRIN DRAXIN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09941)

Host

Rabbit

Contents

NEUCRIN Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

Neucrin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human Neucrin. The immunogen is located within the last 50 amino acids of NEUCRIN.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least three isoforms of Neucrin are known to exist; this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.

Reactive Species

A09941 is reactive to Draxin in Human, Mouse, Rat

Applications

A09941 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

38.363kDa

Background of Draxin/C1orf187

Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures. It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin. Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures. Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Neucrin antibody can be used for detection of Neucrin by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For Draxin (Source: Uniprot.org, NCBI)

Gene Name

Draxin

Full Name

Draxin

Weight

38.363kDa

Superfamily

draxin family

Alternative Names

AGPA3119; C1orf187; chromosome 1 open reading frame 187; dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; Draxin; FLJ34999; MGC117222; Neucrin; UNQ3119 Draxin|2610109H07Rik, Neu, neucrin|dorsal inhibitory axon guidance protein|draxin|dorsal repulsive axon guidance protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Draxin, check out the Draxin Infographic

Draxin infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Draxin: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A09941-0.1 mg

0.1 mg

$449

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