Product Info Summary
SKU: | A05540 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IHC |
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Product info
Product Name
Anti-Neuron Navigator 2 NAV2 Antibody
SKU/Catalog Number
A05540
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Neuron Navigator 2 NAV2 Antibody catalog # A05540. Tested in ELISA, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Neuron Navigator 2 NAV2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05540)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Neuron Navigator 2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05540 is reactive to NAV2 in Human
Applications
A05540 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
268.167kDa
Background of NAV2
Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' By similarity.
Yokota N., Cancer Res. 56:377-383(1996).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
ELISA 1:10000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For NAV2 (Source: Uniprot.org, NCBI)
Gene Name
NAV2
Full Name
Neuron navigator 2
Weight
268.167kDa
Superfamily
Nav/unc-53 family
Alternative Names
EC 3.6.4.12; FLJ10633; FLJ11030; FLJ23707; HELAD1UNC53H2; Helicase APC down-regulated 1; KIAA1419STEERIN2; neuron navigator 2; POMFIL2helicase, APC down-regulated 1; pore membrane and/or filament interacting like protein 2; Pore membrane and/or filament-interacting-like protein 2; RAINB1FLJ77876; retinoic acid inducible gene in neuroblastoma 1; Retinoic acid inducible in neuroblastoma 1; steerin-2; Unc-53 homolog 2; unc53H2 NAV2 HELAD1, POMFIL2, RAINB1, STEERIN2, UNC53H2 neuron navigator 2 neuron navigator 2|helicase, APC down-regulated 1|pore membrane and/or filament-interacting-like protein 2|retinoic acid inducible gene in neuroblastoma 1|steerin-2|unc-53 homolog 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NAV2, check out the NAV2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NAV2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Neuron Navigator 2 NAV2 Antibody (A05540)
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No publications found for A05540
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