Neuron navigator 2 Antibodies

AND NAV2 ELISA kits, Neuron navigator 2 Proteins

Many biological assays use antibodies to detect Neuron navigator 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neuron navigator 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neuron navigator 2 antibodies...

We validate the specificity of these antibodies to Neuron navigator 2 by testing them on tissues known to express NAV2 positively and negatively. Browse below to find the NAV2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Neuron navigator 2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NAV2 IHC Guide

NAV2 Infographic by Boster Bio

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Anti-Neuron Navigator 2 NAV2 Antibody

Human

ELISA, IF, IHC

$380
Cat # A05540
100ul

NAV2 Overview

Facts about Neuron navigator 2.

NAV2 3D structure. Source: alphafold

Neuron navigator 2 (NAV2)

Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of distinct sensory organs.

Gene Information

Human
Gene Name:	NAV2
Uniprot:	Q8IVL1
Entrez:	89797

Family

Belongs to:

Nav/unc-53 family

Alternative Names

EC 3.6.4.12; FLJ10633; FLJ11030; FLJ23707; HELAD1UNC53H2; Helicase APC down-regulated 1; KIAA1419STEERIN2; neuron navigator 2; POMFIL2helicase, APC down-regulated 1; pore membrane and/or filament interacting like protein 2; Pore membrane and/or filament-interacting-like protein 2; RAINB1FLJ77876; retinoic acid inducible gene in neuroblastoma 1; Retinoic acid inducible in neuroblastoma 1; steerin-2; Unc-53 homolog 2; unc53H2

Molecular Weight

Mass (kDA):
268.167 kDA

Genomic Context


Human

Location:	11p15.1
Sequence:	11; NC_000011.10 (19345200..20121601)

Tissue Specificity

Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.

Subcellular Localizations

Nucleus.

Diseases

Influenza
Nervousness
Neuroblastoma
Influenza In Birds
Dental Plaque
Tissue Adhesions
Inflammation
Asymptomatic Infections
Carotid Artery Diseases
Muscular Fasciculation
Influenza Due To Influenza A Virus Subtype H1n1
Colonic Neoplasms
Ataxia

Malignant Tumor Of Colon
Oculocutaneous Albinism Type 2
Carcinoma
Orthomyxoviridae Infections
Cardiovascular Diseases
Malignant Neoplasms
Colonic Diseases, Functional

Interacting Proteins

ADAT2
CFAP58
ING4
ING5
MORF4L1

PIAS2
RBM15
RBM15B

Pathways

Cell Migration
Cell Adhesion
System Development
Axon Guidance
Nervous System Development
Cell Proliferation
Nerve Development
Virulence
Localization
Methylation

Regeneration
Neuroprotection
Cranial Nerve Development
Segmentation

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAV2

References

PMID: 11904404 by Merrill R.A., et al. A mammalian homolog of unc-53 is regulated by all-trans retinoic acid in neuroblastoma cells and embryos.

PMID: 12214280 by Ishiguro H., et al. Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.