Anti-NOG1 GTPBP4 Antibody

Product Name

Anti-NOG1 GTPBP4 Antibody

View all GTPBP4 Antibodies

SKU/Catalog Number

A10450-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-NOG1 GTPBP4 Antibody catalog # A10450-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NOG1 GTPBP4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10450-1)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human NOG1 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A10450-1 is reactive to GTPBP4 in Human, Mouse, Rat

Applications

A10450-1 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

73.964kDa

Background of GTPBP4

Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone By similarity. Possesses negatively supercoiled DNA relaxing activity.

Ng S.-W., Nucleic Acids Res. 27:993-1000(1999).
Kawasaki K., Genome Res. 7:250-261(1997).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000 ELISA 1:5000-20000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For GTPBP4 (Source: Uniprot.org, NCBI)

Alternative Names

Chronic renal failure gene protein; CRFGGTP-binding protein NGB; FLJ10686; FLJ10690; G protein-binding protein CRFG; GTP binding protein 4; NGB; NOG1FLJ39774; nucleolar GTP-binding protein 1 GTPBP4 CRFG, NGB, NOG1 GTP binding protein 4 nucleolar GTP-binding protein 1|G protein-binding protein CRFG|GTP-binding protein NGB|chronic renal failure gene protein

For more info on GTPBP4, check out the GTPBP4 Infographic

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In this infographic, you will see the following information for GTPBP4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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