Anti-Olfactory receptor 2W3 Antibody

OR2W3 antibody

Boster Bio Anti-Olfactory receptor 2W3 Antibody catalog # A12959. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A12959
Size: 100μl
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-Olfactory receptor 2W3 Antibody

View all OR2W3 Antibodies

SKU/Catalog Number

A12959

Size

100μl

Form

Liquid

Description

Boster Bio Anti-Olfactory receptor 2W3 Antibody catalog # A12959. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Olfactory receptor 2W3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12959)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

2H4

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Olfactory receptor 2W3. at AA rangle: 110-190

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12959 is reactive to OR2W3 in Human

Applications

A12959 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

34.789kDa

Background of OR2W3

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

Gene/Protein Information For OR2W3 (Source: Uniprot.org, NCBI)

Gene Name

OR2W3

Full Name

Olfactory receptor 2W3

Weight

34.789kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

olfactory receptor 2W3; Olfactory receptor 2W8; Olfactory receptor OR1-49; olfactory receptor, family 2, subfamily W, member 3 pseudogene; olfactory receptor, family 2, subfamily W, member 3; olfactory receptor, family 2, subfamily W, member 8 pseudogene; OR2W3P; OR2W8P; OST718 OR2W3 OR2W3P, OR2W8P, OST718 olfactory receptor family 2 subfamily W member 3 olfactory receptor 2W3|olfactory receptor 2W8|olfactory receptor OR1-49|olfactory receptor, family 2, subfamily W, member 3 pseudogene|olfactory receptor, family 2, subfamily W, member 8 pseudogene

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on OR2W3, check out the OR2W3 Infographic

OR2W3 infographic

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In this infographic, you will see the following information for OR2W3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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6 Customer Q&As for Anti-Olfactory receptor 2W3 Antibody

Question

We are currently using anti-Olfactory receptor 2W3 antibody A12959 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on zebrafish tissues as well?

Verified Customer

Verified customer

Asked: 2019-12-10

Answer

The anti-Olfactory receptor 2W3 antibody (A12959) has not been validated for cross reactivity specifically with zebrafish tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-12-10

Question

Is a blocking peptide available for product anti-Olfactory receptor 2W3 antibody (A12959)?

Verified Customer

Verified customer

Asked: 2019-09-13

Answer

We do provide the blocking peptide for product anti-Olfactory receptor 2W3 antibody (A12959). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-09-13

Question

Does A12959 anti-Olfactory receptor 2W3 antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?

Verified Customer

Verified customer

Asked: 2019-09-05

Answer

It shows on the product datasheet, A12959 anti-Olfactory receptor 2W3 antibody as been validated on WB. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.

Boster Scientific Support

Answered: 2019-09-05

Question

I was wanting to use your anti-Olfactory receptor 2W3 antibody for WB for human blood on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human blood identification?

Verified Customer

Verified customer

Asked: 2019-08-30

Answer

You can see on the product datasheet, A12959 anti-Olfactory receptor 2W3 antibody has been validated for WB on human tissues. We have an innovator award program that if you test this antibody and show it works in human blood in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2019-08-30

Question

Here is the WB image, lot number and protocol we used for blood using anti-Olfactory receptor 2W3 antibody A12959. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2018-10-09

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2018-10-09

Question

We are interested in to test anti-Olfactory receptor 2W3 antibody A12959 on human blood for research purposes, then I may be interested in using anti-Olfactory receptor 2W3 antibody A12959 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2018-01-08

Answer

The products we sell, including anti-Olfactory receptor 2W3 antibody A12959, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2018-01-08

Order DetailsPrice
A12959

100uL

$399

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