Product Info Summary
SKU: | A07377-1 |
---|---|
Size: | 80 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC-P, WB |
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Product info
Product Name
Anti-ORC3L Antibody (N-term)
SKU/Catalog Number
A07377-1
Size
80 µl
Description
Boster Bio Anti-ORC3L Antibody (N-term) (Catalog # A07377-1). Tested in WB, IHC-P application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-ORC3L Antibody (N-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07377-1)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This ORC3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human ORC3L.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07377-1 is reactive to ORC3 in Human
Reconstitution
Calculated molecular weight
82254 Da
Background of ORC3L
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07377-1 is guaranteed for IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
IHC-P: 1:10-1:50
Validation Images & Assay Conditions
Click image to see more details
ORC3L Antibody (N-term) western blot analysis in SH-SY5Y cell line lysates (35ug/lane). This demonstrates the ORC3L antibody detected the ORC3L protein (arrow).
Click image to see more details
ORC3L Antibody (N-term) (A07377-1)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung adenocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of ORC3L Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Protein Target Info & Infographic
Gene/Protein Information For ORC3 (Source: Uniprot.org, NCBI)
Gene Name
ORC3
Full Name
Origin recognition complex subunit 3
Weight
82254 Da
Superfamily
ORC3 family
Alternative Names
Origin recognition complex subunit 3, Origin recognition complex subunit Latheo, ORC3, LATHEO, ORC3L ORC3 LAT, LATHEOL, ORC3 origin recognition complex subunit 3 origin recognition complex subunit 3|homolog of latheo, Drosophila|origin recognition complex subunit Latheo|origin recognition complex, subunit 3 honolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ORC3, check out the ORC3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ORC3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ORC3L Antibody (N-term) (A07377-1)
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