Product Info Summary
SKU: | A07473S6 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-p52 S6 kinase RPS6KC1 Antibody
SKU/Catalog Number
A07473S6
Size
100ul
Form
Liquid
Description
Boster Bio Anti-p52 S6 kinase RPS6KC1 Antibody catalog # A07473S6. Tested in ELISA, IF, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-p52 S6 kinase RPS6KC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07473S6)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human p52 S6 kinase
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07473S6 is reactive to RPS6KC1 in Human, Mouse
Applications
A07473S6 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
118.682kDa
Background of RPS6KC1
Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.
Nakajima D., DNA Res. 9:99-106(2002).
Olsen J.V., Cell 127:635-648(2006).
Hirosawa M., DNA Res. 6:329-336(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-p52 S6 kinase RPS6KC1 Antibody A07473S6
Western Blot (WB) analysis of HeLa 293T lysis using p52 S6 kinase antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For RPS6KC1 (Source: Uniprot.org, NCBI)
Gene Name
RPS6KC1
Full Name
Ribosomal protein S6 kinase delta-1
Weight
118.682kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.11.1; humS6PKh1; ribosomal protein S6 kinase delta-1; ribosomal protein S6 kinase, 52kD, polypeptide 1,52 kDa ribosomal protein S6 kinase; ribosomal protein S6 kinase, 52kDa, polypeptide 1; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; RPK118; S6K-delta-1; SPHK1-binding protein RPS6KC1 RPK118, RSKL1, S6K-delta-1, S6PKh1, humS6PKh1 ribosomal protein S6 kinase C1 ribosomal protein S6 kinase delta-1|52 kDa ribosomal protein S6 kinase|SPHK1-binding protein|ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein|ribosomal protein S6 kinase, 52kDa, polypeptide 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RPS6KC1, check out the RPS6KC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RPS6KC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-p52 S6 kinase RPS6KC1 Antibody (A07473S6)
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No publications found for A07473S6
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