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Product Info Summary
| SKU: | A05372 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-PCF11 Antibody
SKU/Catalog Number
A05372
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PCF11 Antibody catalog # A05372. Tested in WB applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PCF11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05372)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human KCNK5 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05372 is reactive to PCF11 in Human, Mouse
Applications
A05372 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
173.05kDa
Background of PCF11
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Beebe S.J., Mol. Endocrinol. 4:465-475(1990).
Gregory S.G., Nature 441:315-321(2006).
Wu K.-J., Oncogene 21:7872-7882(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-PCF11 Antibody A05372
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For PCF11 (Source: Uniprot.org, NCBI)
Gene Name
PCF11
Full Name
Pre-mRNA cleavage complex 2 protein Pcf11
Weight
173.05kDa
Alternative Names
KIAA0824PCF11p homolog; PCF11, cleavage and polyadenylation factor II subunit, homolog (S. cerevisiae); PCF11, cleavage and polyadenylation factor II subunit, homolog; PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae); pre-mRNA cleavage complex 2 protein Pcf11; Pre-mRNA cleavage complex II protein Pcf11 PCF11 PCF11 cleavage and polyadenylation factor subunit pre-mRNA cleavage complex 2 protein Pcf11|PCF11, cleavage and polyadenylation factor subunit, homolog|PCF11p homolog|pre-mRNA cleavage complex II protein Pcf11
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PCF11, check out the PCF11 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PCF11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PCF11 Antibody (A05372)
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No publications found for A05372
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