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- Table of Contents
SIRT6 antibody (PB9357) performs well in IHC, WB and shows reactivity with Human, Mouse.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 5 Publications
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Anti-SIRT6Picoband antibody, PB9357, IHC(P)
IHC(P): Mouse Cardiac Muscle Tissue
IHC(P): Mouse Cardiac Muscle Tissue
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Anti-SIRT6 Antibody Picoband®
SIRT6 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse | Rabbit | IHC, WB |
Tested Applications
SIRT6 antibody was positively detected by WB in:
human U87 whole cell, human A549 whole cell, human K562 whole cell, human U2OS whole cell, human Hela whole cell
Suggested blocking solution with 5% non-fat milk or BSA; (*)Recommended protein loading: 20-40 ug per lane
SIRT6 antibody was positively detected by IHC in:
Mouse Cardiac Muscle Tissue, Human Mammary Cancer Tissue
Use TE buffer pH 9.0 for antigen retrieval; (*) citrate buffer pH 6.0 is an alternative.
Recommend Dilution
Application
Dilution
Species
Immunohistochemistry (Paraffin-embedded Section)
0.5-1μg/ml
Human, Mouse
Western blot
0.1-0.5μg/ml
Human
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Reactive Data
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WB
IHC
IF
Human
Tested
Tested
Recommend
Mouse
Tested
Recommend
Monkey
Predicted
Predicted
Predicted
Dog
Predicted
Predicted
Predicted
Sheep
Predicted
Predicted
Predicted
Bovine
Predicted
Predicted
Predicted
Product Information
Product Name
Anti-SIRT6 Antibody Picoband®
View all SIRT6 Antibodies
View all SIRT6 Antibodies
Form
Lyophilized
Uniprot
Gene ID
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Host
Rabbit
Contents
Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg NaN3.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
E.coli-derived human SIRT6 recombinant protein (Position: D14-E180). Human SIRT6 shares 95% amino acid (aa) sequence identity with mouse SIRT6.
Cross-Reactivity
No cross-reactivity with other proteins.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
39-42 kDa
Calculated Molecular Weight
39.1 kDa
Background of SIRT6
SIRT6 is also known as SIR2L6. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
Cite This Product
Anti-SIRT6 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9357)
Antibody Homology Across Species
The results generated by this homology analysis tool for commonly used animal species are shown below. For unlisted species, please refer to the homology analysis between the immunogen sequence and the corresponding species.
A homology of ≥90% is recommended. Generally, higher homology indicates a greater potential for cross-species reactivity. However, protein expression levels may vary among different species, tissues, and cell types. Therefore, the homology analysis results are for reference only and do not guarantee antibody cross-reactivity or experimental performance.
Human
100%
High Homology
Monkey
99%
High Homology
Mouse
95%
High Homology
Dog
94%
High Homology
Sheep
93%
High Homology
Cow
91%
High Homology
Rat
89%
Moderate Homology
Zebrafish
71%
Moderate Homology
Drosophila
50%
Low homology
Homology ≥ 90%High Homology
70% ≤ Homology < 90%Moderate Homology
Homology < 70%Low homology
Protocols
Western Blot protocol for SIRT6 antibody
Immunohistochemistry (IHC) protocol for SIRT6 antibody
Publications
Application:
Species:
miR-33a promotes peri-implantitis by facilitating M1-type polarization of macrophages and inhibiting osteogenesis
Published: 2026-05-04
Journal: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Application: WB
Impact Factor: 3.50
Species: Human
PMID: 42092414
A new mechanism involved in cardiovascular senescence induced by environmentally relevant dose of 16 priority-controlled PAHs
Published: 2025-02-14
Journal: ENVIRONMENT INTERNATIONAL
Application: WB
Impact Factor: 9.70
Species: Rat,Human
PMID: 39970779
Energy Stress-induced CircEPB41(2) Promotes Lipogenesis in Hepatocellular Carcinoma
Published: 2024-12-05
Journal: CANCER RESEARCH
Application: WB
Impact Factor: 12.50
Species: Human
PMID: 39636740
Sirtuin 6 is a key contributor to gender differences in acute kidney injury
Published: 2023-04-25
Journal: Cell Death Discovery
Application: WB,IHC,IF,IP
Impact Factor: 7.00
Species: Human,Mouse
PMID: 37185276
Exogenous Hydrogen Sulfide Ameliorates Diabetic Myocardial Fibrosis by Inhibiting Cell Aging Through SIRT6/AMPK Autophagy
Published: 2020-07-31
Journal: Frontiers in Pharmacology
Application: WB
Impact Factor: 4.23
Species: Rat
PMID: 32903815
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Product Promise
We promise Anti-SIRT6 Antibody Picoband® performs excellently in relevant applications for IHC, WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
Order Product
PB9357
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00
Troubleshooting
Boster Guarantee
Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 14, 2026