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Product Info Summary
| SKU: | A05304 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-PDE8A Antibody
SKU/Catalog Number
A05304
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PDE8A Antibody catalog # A05304. Tested in WB applications. This antibody reacts with Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PDE8A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05304)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CO9A2 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05304 is reactive to PDE8A in Mouse, Rat
Applications
A05304 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
93.304kDa
Background of PDE8A
Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones By similarity.
Fitscher B.A., Biochim. Biophys. Acta 1443:381-385(1998).
Humphray S.J., Nature 429:369-374(2004).
Colinge J., Submitted (OCT-2008) to UniProtKB.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-PDE8A Antibody A05304
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For PDE8A (Source: Uniprot.org, NCBI)
Gene Name
PDE8A
Full Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Weight
93.304kDa
Superfamily
cyclic nucleotide phosphodiesterase family
Alternative Names
cAMP-specific cyclic nucleotide phosphodiesterase 8A; EC 3.1.4.17; FLJ16150; high affinity cAMP-specific and IBMX-insensitive 3'-5'-cyclic phosphodiesterase8A; high-affinity cAMP-specific and IBMX-insensitive 3'-5'-cyclic phosphodiesterase8A; HsT19550; phosphodiesterase 8A PDE8A HsT19550 phosphodiesterase 8A high affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8A|cAMP-specific cyclic nucleotide phosphodiesterase 8A
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PDE8A, check out the PDE8A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PDE8A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PDE8A Antibody (A05304)
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No publications found for A05304
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Customer Reviews
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