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Product Info Summary
| SKU: | A09593 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-PEAR1 Antibody
SKU/Catalog Number
A09593
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PEAR1 Antibody (Catalog # A09593). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PEAR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-PEAR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09593)
Host
Rabbit
Contents
PEAR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
PEAR1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PEAR1. The immunogen is located within the last 50 amino acids of PEAR1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
VEZT antibody is human, mouse and rat reactive. Multiple isoforms are known to exist.
Reactive Species
A09593 is reactive to Pear1 in Human, Mouse, Rat
Applications
A09593 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
110.58kDa
Background of Pear1
Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PEAR1 antibody can be used for detection of PEAR1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PEAR1 in rat kidney tissue lysate with PEAR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of PEAR1 in human kidney tissue with PEAR1 antibody at 2.5 μg/mL.
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Immunofluorescence of PEAR1 in human kidney tissue with PEAR1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Pear1 (Source: Uniprot.org, NCBI)
Gene Name
Pear1
Full Name
Platelet endothelial aggregation receptor 1
Weight
110.58kDa
Superfamily
MEGF family
Alternative Names
Jedi; PEAR1; platelet endothelial aggregation receptor 1 Pear1|3110045G13Rik, Jedi-, Jedi-1, Megf12|platelet endothelial aggregation receptor 1|platelet endothelial aggregation receptor 1|Jedi|jagged and Delta protein|mPEAR1|multiple EGF-like domains protein 12|multiple epidermal growth factor-like domains protein 12|protein Jedi
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Pear1, check out the Pear1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Pear1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PEAR1 Antibody (A09593)
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No publications found for A09593
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Customer Reviews
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