Product Info Summary
SKU: | A02382-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-PFKFB3 Antibody
View all 6 Phosphofructo 2 Kinase Antibodies
SKU/Catalog Number
A02382-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PFKFB3 Antibody catalog # A02382-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PFKFB3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02382-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide from human EYA1/EYA4 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02382-1 is reactive to PFKFB3 in Human, Mouse, Rat
Applications
A02382-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
59.609kDa
Background of 6 Phosphofructo 2 Kinase
Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
Aebi M., Mol. Cell. Biol. 9:5062-5072(1989).
Hattori M., Nature 405:311-319(2000).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunocytochemistry staining of PFKFB3 using Anti-PFKFB3 Antibody (A02382-1).
ICC staining PFKFB3 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeClick image to see more details
Figure 1. Western blotting validation for Anti-PFKFB3 Antibody A02382-1
Western blot analysis of PFKFB3 on different cell lysates using anti-PFKFB3 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For PFKFB3 (Source: Uniprot.org, NCBI)
Gene Name
PFKFB3
Full Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
Weight
59.609kDa
Alternative Names
6 Phosphofructo 2 Kinase; 6PF-2-K/Fru-2,6-P2ase 3,6-bisphosphatase; 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3,6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; FLJ37326; inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; IPFK2; PFK/FBPase 3; PFK2; PFKFB3; Renal carcinoma antigen NY-REN-56 PFKFB3 IPFK2, PFK2, iPFK-2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3|6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase|6PF-2-K/Fru-2,6-P2ase 3|6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme|PFK/FBPase 3|fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase|inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase|renal carcinoma antigen NY-REN-56
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PFKFB3, check out the PFKFB3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PFKFB3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PFKFB3 Antibody (A02382-1)
Hello CJ!
A02382-1 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Zhao Q,Li J,Wu B,Shang Y,Huang X,Dong H,Liu H,Chen W,Gui R,Nie X.Smart Biomimetic Nanocomposites Mediate Mitochondrial Outcome through Aerobic Glycolysis Reprogramming: A Promising Treatment for Lymphoma.ACS Appl Mater Interfaces.2020 May 20;12(20):22687-
Species: Human,Mouse
A02382-1 usage in article: APP:IF, SAMPLE:LYMPHOMA TUMOR TISSUE, DILUTION:NA
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