Product Info Summary
SKU: | A12891 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-PGCC1 FAM120B Antibody
SKU/Catalog Number
A12891
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PGCC1 FAM120B Antibody (Catalog # A12891). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PGCC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-PGCC1 FAM120B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12891)
Host
Rabbit
Contents
PGCC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
SK7
Isotype
IgG
Immunogen
PGCC1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human PGCC1. The immunogen is located within the last 50 amino acids of PGCC1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody will not cross-react with FAM120A.
Reactive Species
A12891 is reactive to Fam120b in Human, Mouse, Rat
Applications
A12891 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
89.313kDa
Background of Fam120b
The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PGCC1 antibody can be used for detection of PGCC1 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of PGCC1 in rat thymus tissue lysate with PGCC1 antibody at (A) 0.5 and (B) 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Fam120b (Source: Uniprot.org, NCBI)
Gene Name
Fam120b
Full Name
Constitutive coactivator of peroxisome proliferator-activated receptor gamma
Weight
89.313kDa
Superfamily
constitutive coactivator of PPAR-gamma family
Alternative Names
CCPGKIAA0183; Constitutive coactivator of PPARG; Constitutive coactivator of PPAR-gamma; family with sequence similarity 120B; FLJ55614; KIAA1838constitutive coactivator of peroxisome proliferator-activated receptor gamma; PGCC1dJ894D12.1; PPARG constitutive coactivator 1; PPARgamma constitutive coactivator 1; Protein FAM120B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Fam120b, check out the Fam120b Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Fam120b: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PGCC1 FAM120B Antibody (A12891)
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