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Product Info Summary
| SKU: | A04412S674 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Phospho-MLK3 (S674) MAP3K11 Antibody
SKU/Catalog Number
A04412S674
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-MLK3 (S674) MAP3K11 Antibody catalog # A04412S674. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-MLK3 (S674) MAP3K11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04412S674)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human MLK3 around the phosphorylation site of S674.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04412S674 is reactive to MAP3K11 in Human, Mouse, Rat
Applications
A04412S674 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
92.688kDa
Background of MLK3
Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.
Kikuno R., DNA Res. 6:197-205(1999).
Bechtel S., BMC Genomics 8:399-399(2007).
Heilig R., Nature 421:601-607(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:5000
Validation Images & Assay Conditions
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Western blot analysis of extracts from NIH-3T3 cells, using Phospho-MLK3 (S674) Polyclonal Antibody.
Protein Target Info & Infographic
Gene/Protein Information For MAP3K11 (Source: Uniprot.org, NCBI)
Gene Name
MAP3K11
Full Name
Mitogen-activated protein kinase kinase kinase 11
Weight
92.688kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.11; EC 2.7.11.25; MAP3K11; MEKK11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; MLK3; MLK3MLK-3; PTK1; PTK1protein-tyrosine kinase PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; SPRKMGC17114; Src-homology 3 domain-containing proline-rich kinase MAP3K11 MEKK11, MLK-3, MLK3, PTK1, SPRK mitogen-activated protein kinase kinase kinase 11 mitogen-activated protein kinase kinase kinase 11|SH3 domain-containing proline-rich kinase|mixed lineage kinase 3|protein-tyrosine kinase PTK1|src-homology 3 domain-containing proline-rich kinase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MAP3K11, check out the MAP3K11 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MAP3K11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-MLK3 (S674) MAP3K11 Antibody (A04412S674)
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No publications found for A04412S674
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