Product Info Summary
SKU: | A02155S43 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC |
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Product info
Product Name
Anti-Phospho-NACA (S43) Antibody
SKU/Catalog Number
A02155S43
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-NACA (S43) Antibody catalog # A02155S43. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-NACA (S43) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02155S43)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human NACA around the phosphorylation site of S43.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02155S43 is reactive to NACA in Human, Mouse, Rat
Applications
A02155S43 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
205.422kDa
Background of NACA1
Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.
Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).
Ruppert S., Nature 362:175-179(1993).
Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
ELISA 1:5000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For NACA (Source: Uniprot.org, NCBI)
Gene Name
NACA
Full Name
Nascent polypeptide-associated complex subunit alpha, muscle-specific form
Weight
205.422kDa
Alternative Names
Allergen Hom s 2; alpha-NAC; MGC117224; NACA1; NAC-alpha; nascent polypeptide-associated complex alpha subunit; nascent polypeptide-associated complex subunit alpha; nascent-polypeptide-associated complex alpha polypeptide NACA HSD48, NAC-alpha1, skNAC, NACA nascent polypeptide associated complex subunit alpha nascent polypeptide-associated complex subunit alpha|alpha-NAC, muscle-specific form|nascent-polypeptide-associated complex alpha polypeptide
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NACA, check out the NACA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NACA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-NACA (S43) Antibody (A02155S43)
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