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Product Info Summary
| SKU: | A02788S44 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC |
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Product info
Product Name
Anti-Phospho-ROM-K (S44) KCNJ1 Antibody
SKU/Catalog Number
A02788S44
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-ROM-K (S44) KCNJ1 Antibody catalog # A02788S44. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-ROM-K (S44) KCNJ1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02788S44)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ROM-K around the phosphorylation site of S44.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02788S44 is reactive to KCNJ1 in Human, Mouse, Rat
Applications
A02788S44 is guaranteed for ELISA, IF, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
44.795kDa
Background of KCNJ1
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARFof CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARFof CDKN2A By similarity. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Hiroyasu Inada, J. Cell Biol., Oct 2001; 155: 415.
Kenneth M. Izumi, Mol. Cell. Biol., Aug 1999; 19: 5759 - 5767.
Susumu Rokudai, Mol. Cell. Biol., Dec 2002; 22: 8695 - 8708.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For KCNJ1 (Source: Uniprot.org, NCBI)
Gene Name
KCNJ1
Full Name
ATP-sensitive inward rectifier potassium channel 1
Weight
44.795kDa
Superfamily
inward rectifier-type potassium channel (TC 1.A.2.1) family
Alternative Names
ATP-regulated potassium channel ROM-K; ATP-sensitive inward rectifier potassium channel 1; inwardly rectifying K+ channel; KIR1.1; potassium inwardly-rectifying channel, subfamily J, member 1; ROMK1inwardly rectifying subfamily J member 1 KCNJ1 KIR1.1, ROMK, ROMK1 potassium inwardly rectifying channel subfamily J member 1 ATP-sensitive inward rectifier potassium channel 1|ATP-regulated potassium channel ROM-K|inward rectifier K(+) channel Kir1.1|inwardly rectifying K+ channel|potassium channel, inwardly rectifying subfamily J member 1|potassium voltage-gated channel subfamily J member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCNJ1, check out the KCNJ1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCNJ1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-ROM-K (S44) KCNJ1 Antibody (A02788S44)
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No publications found for A02788S44
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