Anti-Phospho-T beta (S142) THRB Antibody

Product Name

Anti-Phospho-T beta (S142) THRB Antibody

View all TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibodies

SKU/Catalog Number

A01181S142

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Phospho-T beta (S142) THRB Antibody catalog # A01181S142. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Phospho-T beta (S142) THRB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01181S142)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human TRbeta1 around the phosphorylation site of S142.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01181S142 is reactive to THRB in Human, Mouse, Rat

Applications

A01181S142 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

52.788kDa

Background of TR beta 1/NR1A2/Thyroid Hormone Receptor beta

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

ShunJiang Yu, J. Biol. Chem., May 2003; 278: 19597 - 19602.
TT Chen, Mol. Cell. Biol., Jun 1997; 17: 3056 - 3064.
Oscar B. Goodman, J. Biol. Chem., Oct 1995; 270: 23768.
Didier Jean, J. Biol. Chem., Jun 1998; 273: 16501

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
ELISA 1:5000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For THRB (Source: Uniprot.org, NCBI)

Alternative Names

avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2; c-erbA-2; c-erbA-beta; ERBA2MGC126109; ERBA-BETA; GRTH; MGC126110; NR1A2; NR1A2thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog 2); Nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; THR1pituitary resistance to thyroid hormone; THRB; THRB1; THRB2; thyroid hormone receptor beta 1; thyroid hormone receptor beta; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a)oncogene homolog 2, avian); TR beta 1; v-ErbA2 THRB C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR11, THRB2, THRB thyroid hormone receptor beta thyroid hormone receptor beta|nuclear receptor subfamily 1 group A member 2|oncogene ERBA2|thyroid hormone nuclear receptor beta variant 1|thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)

For more info on THRB, check out the THRB Infographic

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In this infographic, you will see the following information for THRB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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