Anti-Plexin-A4 PLXNA4 Antibody

Plexin A4 antibody

Boster Bio Anti-Plexin-A4 PLXNA4 Antibody catalog # A05461. Tested in WB applications. This antibody reacts with Mouse,Rat.

Product Info Summary

SKU: A05461
Size: 100ul
Reactive Species: Mouse, Rat
Host: Rabbit
Application: WB

Product Name

Anti-Plexin-A4 PLXNA4 Antibody

View all Plexin A4 Antibodies

SKU/Catalog Number

A05461

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Plexin-A4 PLXNA4 Antibody catalog # A05461. Tested in WB applications. This antibody reacts with Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Plexin-A4 PLXNA4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05461)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human PNPase

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05461 is reactive to PLXNA4 in Mouse, Rat

Applications

A05461 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

212.455kDa

Background of Plexin A4

Isoform GANP:Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells By similarity. Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Isoform MCM3AP:Acetyltransferase targeting MCM3. Inhibits initiation of DNA replication, but not elongation.

Nobuo Sakaguchi, J. Immunol., Apr 2005; 174: 4485 - 4494.
Kazuhiko Kuwahara, Blood, Apr 2000; 95: 2321 - 2328.
Y Kono, K Maeda, Genes Cells, Aug 2002; 7: 821 - 834.
Kazuhiko Kuwahara, PNAS, Aug 2001; 98: 10279.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000

Validation Images & Assay Conditions

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Gene/Protein Information For PLXNA4 (Source: Uniprot.org, NCBI)

Gene Name

PLXNA4

Full Name

Plexin-A4

Weight

212.455kDa

Superfamily

plexin family

Alternative Names

A; DKFZp434G0625; FAYV2820; FLJ35026; FLJ38287; KIAA1550DKFZp566O0546; PLEXA4; Plexin A4; plexin A4, B; plexin-A4; PLXNA4; PLXNA4A; PLXNA4B; PRO34003 PLXNA4 FAYV2820, PLEXA4A, PLXNA4B, PRO34003, PLXNA4 plexin A4 plexin-A4|epididymis secretory sperm binding protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PLXNA4, check out the PLXNA4 Infographic

PLXNA4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PLXNA4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A05461-100ul

100ul

$405

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