Product Info Summary
SKU: | M00516-3 |
---|---|
Size: | 100 μl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IP, WB |
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Product info
Product Name
Anti-PON1 Monoclonal Antibody
SKU/Catalog Number
M00516-3
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-PON1 Monoclonal Antibody catalog # M00516-3. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PON1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00516-3)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
ACAG-16
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human PON1 Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00516-3 is reactive to PON1 in Human, Mouse, Rat
Applications
M00516-3 is guaranteed for IP, WB Boster Guarantee
Observed Molecular Weight
61 kDa
Calculated molecular weight
33304 MW
Background of PON1
Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:1000-1:5000
IP 1:50
Validation Images & Assay Conditions
![m00516 3 wb m00516 3 wb](https://www.bosterbio.com/media/catalog/product/m/0/m00516-3-wb.jpg)
Click image to see more details
Western blot analysis of PON1 expression in human plasma lysate.
Protein Target Info & Infographic
Gene/Protein Information For PON1 (Source: Uniprot.org, NCBI)
Gene Name
PON1
Full Name
Serum paraoxonase/arylesterase 1
Weight
33304 MW
Superfamily
paraoxonase family
Alternative Names
A-esterase 1; Aromatic esterase 1; arylesterase B-type; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; ESA; ESAesterase A; K-45; MVCD5; paraoxonase 1; PON 1; PON1; PONparaoxonase B-type; serum aryldiakylphosphatase; Serum aryldialkylphosphatase 1; serum paraoxonase/arylesterase 1 PON1 ESA, MVCD5, PON paraoxonase 1 serum paraoxonase/arylesterase 1|A-esterase 1|K-45|PON 1|aromatic esterase 1|arylesterase 1|arylesterase B-type|esterase A|paraoxonase B-type|serum aryldiakylphosphatase|serum aryldialkylphosphatase 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PON1, check out the PON1 Infographic
![PON1 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PON1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PON1 Monoclonal Antibody (M00516-3)
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