Anti-PON1 Antibody

PON1 antibody

Boster Bio Anti-PON1 Antibody catalog # PA2253. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA2253
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-PON1 Antibody

View all PON1 Antibodies

SKU/Catalog Number

PA2253

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-PON1 Antibody catalog # PA2253. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PON1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2253)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human PON1, different from the related mouse and rat sequences by three amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2253 is reactive to PON1 in Human, Mouse, Rat

Applications

PA2253 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

40 kDa

Calculated molecular weight

39.731kDa

Background of PON1

Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-gamma, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For PON1 (Source: Uniprot.org, NCBI)

Gene Name

PON1

Full Name

Serum paraoxonase/arylesterase 1

Weight

39.731kDa

Superfamily

paraoxonase family

Alternative Names

A-esterase 1; Aromatic esterase 1; arylesterase B-type; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; ESA; ESAesterase A; K-45; MVCD5; paraoxonase 1; PON 1; PON1; PONparaoxonase B-type; serum aryldiakylphosphatase; Serum aryldialkylphosphatase 1; serum paraoxonase/arylesterase 1 PON1 ESA, MVCD5, PON paraoxonase 1 serum paraoxonase/arylesterase 1|A-esterase 1|K-45|PON 1|aromatic esterase 1|arylesterase 1|arylesterase B-type|esterase A|paraoxonase B-type|serum aryldiakylphosphatase|serum aryldialkylphosphatase 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PON1, check out the PON1 Infographic

PON1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PON1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-PON1 Antibody

Question

We are currently using anti-PON1 antibody PA2253 for mouse tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on horse tissues as well?

Verified Customer

Verified customer

Asked: 2019-12-24

Answer

The anti-PON1 antibody (PA2253) has not been validated for cross reactivity specifically with horse tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-12-24

Order DetailsPrice
PA2253

100μg

$370
PA2253-10ug

10μg sample (liquid)

$99
PA2253-Biotin

100 μg Biotin conjugated

$570
PA2253-Cy3

100 μg Cy3 conjugated

$570
PA2253-Dylight488

100 μg Dylight488 conjugated

$570
PA2253-Dylight550

100 μg Dylight550 conjugated

$570
PA2253-Dylight594

100 μg Dylight594 conjugated

$570
PA2253-FITC

100 μg FITC conjugated

$570
PA2253-HRP

100 μg HRP conjugated

$570
PA2253-APC

100 μg APC conjugated

$670
PA2253-PE

100 μg PE conjugated

$670
PA2253-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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PA2253
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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