Anti-PP4R2 PPP4R2 Antibody

PPP4R2 antibody

Boster Bio Anti-PP4R2 PPP4R2 Antibody (Catalog # A10882). Tested in WB applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A10882
Size: 100 µl
Reactive Species: Human, Mouse
Host: Rabbit
Application: WB

Product Name

Anti-PP4R2 PPP4R2 Antibody

View all PPP4R2 Antibodies

SKU/Catalog Number

A10882

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-PP4R2 PPP4R2 Antibody (Catalog # A10882). Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PP4R2 PPP4R2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10882)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human PP4R2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A10882 is reactive to PPP4R2 in Human, Mouse

Applications

A10882 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

46.898kDa

Background of PPP4R2

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair.

Hastie C.J., Biochem. J. 347:845-855(2000).
Zhang W., Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Mural R.J., Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For PPP4R2 (Source: Uniprot.org, NCBI)

Gene Name

PPP4R2

Full Name

Serine/threonine-protein phosphatase 4 regulatory subunit 2

Weight

46.898kDa

Superfamily

PPP4R2 family

Alternative Names

MGC131930; PP4R2; protein phosphatase 4, regulatory subunit 2; serine/threonine-protein phosphatase 4 regulatory subunit 2 PPP4R2 PP4R2 protein phosphatase 4 regulatory subunit 2 serine/threonine-protein phosphatase 4 regulatory subunit 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PPP4R2, check out the PPP4R2 Infographic

PPP4R2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PPP4R2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-PP4R2 PPP4R2 Antibody

Question

We are currently using anti-PP4R2 antibody A10882 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, mouse. Is it possible that the antibody can work on pig tissues as well?

Verified Customer

Verified customer

Asked: 2019-07-12

Answer

The anti-PP4R2 antibody (A10882) has not been tested for cross reactivity specifically with pig tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-07-12

Question

Would anti-PP4R2 antibody A10882 work on canine WB with cervix carcinoma?

E. Parker

Verified customer

Asked: 2015-03-19

Answer

Our lab technicians have not validated anti-PP4R2 antibody A10882 on canine. You can run a BLAST between canine and the immunogen sequence of anti-PP4R2 antibody A10882 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated canine samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in canine cervix carcinoma in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2015-03-19

Question

Our lab want to know about to test anti-PP4R2 antibody A10882 on human uterus for research purposes, then I may be interested in using anti-PP4R2 antibody A10882 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

N. Carter

Verified customer

Asked: 2015-03-16

Answer

The products we sell, including anti-PP4R2 antibody A10882, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2015-03-16

Order DetailsPrice
A10882-100uL

100uL

$360

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