Anti-PPM1L/Pp2C Epsilon Antibody

Product Name

Anti-PPM1L/Pp2C Epsilon Antibody

View all PP2C epsilon/PPM1L Antibodies

SKU/Catalog Number

A11054

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-PPM1L/Pp2C Epsilon Antibody (Catalog # A11054). Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PPM1L/Pp2C Epsilon Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11054)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human PPM1L.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A11054 is reactive to PPM1L in Human, Mouse

Applications

A11054 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

41.053kDa

Background of PP2C epsilon/PPM1L

Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.

Jin F., Mol. Biol. Rep. 31:197-202(2004).
Ota T., Nat. Genet. 36:40-45(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from Jurkat cells, using PPM1L antibody A11054.

Gene/Protein Information For PPM1L (Source: Uniprot.org, NCBI)

Alternative Names

EC 3.1.3; EC 3.1.3.16; MGC132545; MGC132547; PP2C epsilon; PP2CE; PP2CEProtein phosphatase 2C isoform epsilon; PP2C-epsilon; PPM1L; PPM1-LIKE; protein phosphatase 1 (formerly 2C)-like; protein phosphatase 1L; Protein phosphatase 1-like; Protein phosphatase 2C epsilon isoform; protein phosphatase, Mg2+/Mn2+ dependent, 1L PPM1L PP2C-epsilon, PP2CE, PPM1-LIKE protein phosphatase, Mg2+/Mn2+ dependent 1L protein phosphatase 1L|PP2C epsilon

For more info on PPM1L, check out the PPM1L Infographic

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In this infographic, you will see the following information for PPM1L: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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