Anti-PRKAA2 Antibody

AMPK alpha 2 antibody

Boster Bio Anti-PRKAA2 Antibody (Catalog # M01420). Tested in IF, WB application(s). This antibody reacts with Human.

Product Info Summary

SKU: M01420
Size: 80 µl
Reactive Species: Human
Host: Mouse
Application: IF, WB

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Product Name

Anti-PRKAA2 Antibody

View all AMPK alpha 2 Antibodies

SKU/Catalog Number

M01420

Size

80 µl

Description

Boster Bio Anti-PRKAA2 Antibody (Catalog # M01420). Tested in IF, WB application(s). This antibody reacts with Human.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-PRKAA2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01420)

Host

Mouse

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Monoclonal

Clone Number

206CT5.4.2

Isotype

IgG2a,K

Immunogen

This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01420 is reactive to PRKAA2 in Human

Applications

M01420 is guaranteed for IF, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

62.32kDa

Background of AMPK alpha 2

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IF: 1:10-1:50
WB: 1:1000

Validation Images & Assay Conditions

Gene/Protein Information For PRKAA2 (Source: Uniprot.org, NCBI)

Gene Name

PRKAA2

Full Name

5'-AMP-activated protein kinase catalytic subunit alpha-2

Weight

62.32kDa

Superfamily

protein kinase superfamily

Alternative Names

5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK alpha 2; AMPK subunit alpha-2; AMPK2; AMPK5'-AMP-activated protein kinase, catalytic alpha-2 chain; AMPK-alpha-2 chain; EC 2.7.11; EC 2.7.11.1; PRKAA; PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit PRKAA2 AMPK, AMPK2, AMPKa2, PRKAA protein kinase AMP-activated catalytic subunit alpha 2 5-AMP-activated protein kinase catalytic subunit alpha-2|5-AMP-activated protein kinase, catalytic alpha-2 chain|ACACA kinase|AMP-activated protein kinase alpha-2 subunit variant 2|AMP-activated protein kinase alpha-2 subunit variant 3|AMPK alpha 2|AMPK subunit alpha-2|AMPK-alpha-2 chain|HMGCR kinase|acetyl-CoA carboxylase kinase|hydroxymethylglutaryl-CoA reductase kinase|protein kinase, AMP-activated, alpha 2 catalytic subunit

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PRKAA2, check out the PRKAA2 Infographic

PRKAA2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PRKAA2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01420-80ul

80 µl

$298
M01420-400ul

400 µl

$460

Free Secondary Antibody

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M01420
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$298.00

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