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Product Info Summary
| SKU: | A08591 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Probable ribonuclease ZC3H12D ZC3H12D Antibody
SKU/Catalog Number
A08591
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Probable ribonuclease ZC3H12D ZC3H12D Antibody (Catalog # A08591). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
ZC3H12D antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Probable ribonuclease ZC3H12D ZC3H12D Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08591)
Host
Rabbit
Contents
ZC3H12D Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZC3H12D antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZC3H12D. The immunogen is located within amino acids 280 - 330 of ZC3H12D.
Reactive Species
A08591 is reactive to ZC3H12D in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
58.1 kDa
Background of ZC3H12D
ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08591 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZC3H12D antibody can be used for detection of ZC3H12D by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZC3H12D in human spleen tissue lysate with ZC3H12D antibody at 1 μg/mL.
Specific Publications For Anti-Probable ribonuclease ZC3H12D ZC3H12D Antibody (A08591)
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